Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
TREM receptor
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "TREM receptor" in MCE Product Catalog:
8
Research Areas:
8
Research Areas:
5
3
Target:
Research Areas:
3
Target:
Research Areas:
Cat. No.: HY-175510
CAS No.: 3114105-24-4
Target:
Research Areas:
TREM2 agonist-5 is the microglial lipid-sensing receptor (TREM2) agonist with a Kd of 71.36 μM. TREM2 agonist-5 is a racemic structural analog of the TREM2 agonist VG-3927 and exhibits superior microglial phagocytosis and activates TREM2 signaling in HEK293-hTREM2/DAP12 cells. TREM2 agonist-5 displays a superior in vitro pharmacokinetic profile to VG-3927. TREM2 agonist-5 can used for the study of Alzheimer’s disease .
Cat. No.: HY-P990043
CAS No.: 2733621-19-5
Synonyms: VGL101
Target:
Research Areas:
Cat. No.: HY-178324
CAS No.: 364611-21-2
Target:
Research Areas:
T2M-010 is a potent, brain-penetrant TREM2 agonist (Kd = 0.83 μM). T2M-010 activates receptor-proximal signaling, inducing SYK phosphorylation in TREM2-expressing cells, and promotes microglial phagocytosis. T2M-010 can be used for the study of protective microglial responses relevant to Alzheimer’s disease (AD) .
Cat. No.: HY-169859
CAS No.: 3035217-40-1
Research Areas:
EP4 receptor antagonist 7 (Compound 14) is an antagonist of the prostaglandin E2 (PGE2) receptor subtype EP4 with an IC50 value of 1.1 nM. EP4 receptor antagonist 7 inhibits PGE2-induced β-arrestin recruitment in HEK293 cells with an IC50 value of 0.9 nM. EP4 receptor antagonist 7 decreases PGE2-induced expression of mRNA encoding IL-4, macrophage mannose receptor 1 (Mrc1), chitinase-like protein 3 (Chil3), chemokine (C-X-C) motif ligand 1 (Cxcl1), triggering receptor expressed on myeloid cells 2 (Trem2), and arginase-1 (Arg1), in RAW 264.7 macrophages. EP4 receptor antagonist 7 combined with an anti-PD-1 antibody inhibits tumor growth and increases infiltration of CD 8+ T cells into tumors in a CT26 murine colon cancer model .
Cat. No.: HY-P10220
CAS No.: 2914099-35-5
Research Areas:
Cat. No.: HY-182756
CAS No.: 3070235-71-8
Target:
Research Areas:
TREM2 modulator-1 is a TREM2 modulator with an EC50 categorized as A and Emax of ++, and can be found in relevant research contexts. TREM2 modulator-1 modulates Triggering Receptor Expressed on Myeloid Cells 2. TREM2 modulator-1 can be used for the research of neurodegenerative diseases .
Cat. No.: HY-P70534
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TREM2; TREM2b; Triggering receptor Expressed On Myeloid Cells 2; TREM2c; TREM-2; Triggering receptor Expressed On Myeloid Cells 2a; Triggering receptor Expressed On Monocytes 2; PLOSL2; TREM2a; AD17
Cat. No.: HY-P71381
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TREM2; TREM2b; Triggering receptor Expressed On Myeloid Cells 2; TREM2c; TREM-2; Triggering receptor Expressed On Myeloid Cells 2a; Triggering receptor Expressed On Monocytes 2; PLOSL2; TREM2a; AD17
Cat. No.: HY-P72438
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TREM2; TREM2b; Triggering receptor Expressed On Myeloid Cells 2; TREM2c; TREM-2; Triggering receptor Expressed On Myeloid Cells 2a; Triggering receptor Expressed On Monocytes 2; PLOSL2; TREM2a; AD17
Species:
Source:
Cat. No.: HY-P704940
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TREM2; TREM2b; Triggering receptor Expressed On Myeloid Cells 2; TREM2c; TREM-2; Triggering receptor Expressed On Myeloid Cells 2a; Triggering receptor Expressed On Monocytes 2; PLOSL2; TREM2a; AD17
Cat. No.: HY-P704937
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TREM2; TREM2b; Triggering receptor Expressed On Myeloid Cells 2; TREM2c; TREM-2; Triggering receptor Expressed On Myeloid Cells 2a; Triggering receptor Expressed On Monocytes 2; PLOSL2; TREM2a; AD17
Cat. No.: HY-P704938
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TREM2; TREM2b; Triggering receptor Expressed On Myeloid Cells 2; TREM2c; TREM-2; Triggering receptor Expressed On Myeloid Cells 2a; Triggering receptor Expressed On Monocytes 2; PLOSL2; TREM2a; AD17
Cat. No.: HY-P78222
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TREM2; TREM2b; Triggering receptor Expressed On Myeloid Cells 2; TREM2c; TREM-2; Triggering receptor Expressed On Myeloid Cells 2a; Triggering receptor Expressed On Monocytes 2; PLOSL2; TREM2a; AD17
Cat. No.: HY-P704939
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TREM2; TREM2b; Triggering receptor Expressed On Myeloid Cells 2; TREM2c; TREM-2; Triggering receptor Expressed On Myeloid Cells 2a; Triggering receptor Expressed On Monocytes 2; PLOSL2; TREM2a; AD17
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
