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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
TWEAK
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "TWEAK" in MCE Product Catalog:
5
Research Areas:
Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs, with IC50s of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively . Aurintricarboxylic acid is a potent anti-influenza agent by directly inhibiting the neuraminidase . Aurintricarboxylic acid is an inhibitor of topoisomerase II and apoptosis . Aurintricarboxylic acid is a selective inhibitor of the TWEAK-Fn14 signaling pathway . Aurintricarboxylic acid also acts as a cystathionine-lyase (CSE) inhibitor with an IC50 of 0.6 μM . Aurintricarboxylic acid is a modifier of miRNAs that regulate miRNA function, with an IC50 of 0.47 µM .
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3 Cited Publications
Cat. No.: HY-P7309
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor Necrosis Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of Apoptosis; APO3L; Tumor Necrosis Factor Ligand 4A; Tumor Necrosis Factor Ligand Superfamily Member 12; HCG1991317, Is
1
1 Cited Publications
Cat. No.: HY-P72434
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF12A; Tumor Necrosis Factor Receptor Superfamily Member 12A; TNF Receptor Superfamily Member 12A; FGF-Inducible 14; TWEAKR; TWEAK-Receptor; FN14; Tumor Necrosis Factor Receptor Superfamily, Member 12A; CD266; Type I Transmembrane Protein Fn14; Fibrob
Cat. No.: HY-P99361
CAS No.: 1062149-33-0
Synonyms: PDL192; ABT-361; Anti-TNFRSF12A/TWEAKR/CD266 Reference Antibody (enavatuzumab)
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Cat. No.: HY-113763
CAS No.: 951612-19-4
Target:
Research Areas:
L524-0366 is a specific, dose-dependent TWEAK-Fn14 inhibitor. L524-0366 specifically binds to the Fn14 surface with a KD of 7.12 μM, competitively inhibiting the binding of Fn14 to TWEAK (inhibition rate reaching 16%). L524-0366 inhibits TWEAK-induced glioma cell migration without potential cytotoxic effects .
Cat. No.: HY-P990657
Synonyms: RO5458640
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Cat. No.: HY-RS14822
Target:
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TNFSF12 Human Pre-designed siRNA Set A contains three designed siRNAs for TNFSF12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P992321
Target:
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Cat. No.: HY-P700229AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor Necrosis Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of Apoptosis; APO3L; Tumor Necrosis Factor Ligand 4A; Tumor Necrosis Factor Ligand Superfamily Member 12; HCG1991317, Is
Cat. No.: HY-P701045
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor Necrosis Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of Apoptosis; APO3L; Tumor Necrosis Factor Ligand 4A; Tumor Necrosis Factor Ligand Superfamily Member 12; HCG1991317, Is
Cat. No.: HY-P77263
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor Necrosis Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of Apoptosis; APO3L; Tumor Necrosis Factor Ligand 4A; Tumor Necrosis Factor Ligand Superfamily Member 12; HCG1991317, Is
Species:
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Cat. No.: HY-P77264
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor Necrosis Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of Apoptosis; APO3L; Tumor Necrosis Factor Ligand 4A; Tumor Necrosis Factor Ligand Superfamily Member 12; HCG1991317, Is
Cat. No.: HY-P77265
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor Necrosis Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of Apoptosis; APO3L; Tumor Necrosis Factor Ligand 4A; Tumor Necrosis Factor Ligand Superfamily Member 12; HCG1991317, Is
Cat. No.: HY-P77266
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor Necrosis Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of Apoptosis; APO3L; Tumor Necrosis Factor Ligand 4A; Tumor Necrosis Factor Ligand Superfamily Member 12; HCG1991317, Is
Cat. No.: HY-P701323
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor Necrosis Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of Apoptosis; APO3L; Tumor Necrosis Factor Ligand 4A; Tumor Necrosis Factor Ligand Superfamily Member 12; HCG1991317, Is
Cat. No.: HY-P700156AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor Necrosis Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of Apoptosis; APO3L; Tumor Necrosis Factor Ligand 4A; Tumor Necrosis Factor Ligand Superfamily Member 12; HCG1991317, Is
Cat. No.: HY-RS23543
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Tnfsf12 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tnfsf12 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17099
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Tnfsf12 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tnfsf12 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
