951612-19-4
951612-19-4
Chemical Structure
L524-0366
- CAS No.: 951612-19-4
- Formula:C13H13ClN4OS
- Molecular Weight:308.79
IUPAC Name: (1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)(thiomorpholino)methanone
InChIKey: ZOBDTKWDYMRKPF-UHFFFAOYSA-N
SMILES: O=C(N1CCSCC1)C2=CN(N=N2)C3=CC=CC(Cl)=C3
Biological Activity: L524-0366 is a specific, dose-dependent TWEAK-Fn14 inhibitor. L524-0366 specifically binds to the Fn14 surface with a KD of 7.12 μM, competitively inhibiting the binding of Fn14 to TWEAK (inhibition rate reaching 16%). L524-0366 inhibits TWEAK-induced glioma cell migration without potential cytotoxic effects[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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L524-0366 | 99.95% | L524-0366 is a specific, dose-dependent TWEAK-Fn14 inhibitor. L524-0366 specifically binds to the Fn14 surface with a KD of 7.12 μM, competitively inhibiting the binding of Fn14 to TWEAK (inhibition rate reaching 16%). L524-0366 inhibits TWEAK-induced glioma cell migration without potential cytotoxic effects. | ||||||||||||||||||||
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