1 Result for "

Trifunctional Pt(II) complex

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Trifunctional Pt(II) complex" in MCE Product Catalog:

Cat. No.: HY-146194
CAS No.: 2974448-39-8
Research Areas:  

Cancer

NHEJ inhibitor-1 (Compound C2) is a trifunctional Pt(II) complex, alleviates the non-homologous end connection (NHEJ)/homologous recombination (HR)-related double strand breaks (DSBs) repairs to evade Cisplatin-resistance in non-small cell lung cancer (NSCLC). NHEJ inhibitor-1 inhibits the damage repair proteins Ku70 and Rad51 to make tumors re-sensitive to Cisplatin. NHEJ inhibitor-1 also induces ROS generation and MMP deduction .
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