1 Result for "

VU 10010

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VU 10010" in MCE Product Catalog:

Cat. No.: HY-14563
CAS No.: 633283-39-3
Purity:  98.70%
Target:  

mAChR

Research Areas:  

Neurological Disease

VU10010 is a potent, highly selective and allosteric M4 mAChR potentiator with an EC50 of 400 nM. VU10010 binds to an allosteric site on M4 mAChR and increases affinity for acetylcholine and coupling to G proteins. VU10010 increases carbachol-induced depression of transmission at excitatory but not inhibitory synapses in the hippocampus .
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