1 Result for "

VU0546110

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VU0546110" in MCE Product Catalog:

Cat. No.: HY-164911
CAS No.: 1421523-00-3
Target:  

Potassium Channel

Research Areas:  

Endocrinology

VU0546110 is a selective inhibitor of the sperm-specific potassium channel SLO3, with IC50s of 1.287 μM (SLO3) and 59.80 μM (SLO1) in HEK293 cells, respectively. VU0546110 blocks heterologous SLO3 currents and endogenous K + currents in human sperm. VU0546110 halts sperm hyperpolarization, induced acrosome reaction, and hyper-activated motility. VU0546110 has contraceptive potential .
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