Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
Valsa mali
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "Valsa mali" in MCE Product Catalog:
Category:
Alkaloids Simaroubaceae Other Diseases Pyridine Alkaloids Plants Disease Research Fields Indole Alkaloids
Target:
Pectate Lyase is an enzyme that exists in microorganisms, plants and animals. Pectate Lyase degrades pectic acid via the β-elimination mechanism. Pectate Lyase induces plant immune responses and participates in virulence. Pectate Lyase is applied in fields such as plant fiber degumming and fruit and vegetable processing .
Cat. No.: HY-174831
Target:
Research Areas:
SDH-IN-28 is a succinate dehydrogenase inhibitor with an IC50 value of 2.65 mg/L. SDH-IN-28 demonstrates broad-spectrum fungicidal efficacy, with EC50 values of 0.21 (Valsa mali), 0.95 (Botrytis cinerea), 0.64 (Rhizoctonia solani), 1.33 (Fusarium graminearum), and 0.66 mg/L (Gaeumannomyces graminis). SDH-IN-28 effectively prevents V. mali infection in apples .
Chitin synthase inhibitor 4 (compound 4fh) is a chitin synthase inhibitor with fungicidal effect. Chitin synthase inhibitor 4 is a potential chitin synthase-based fungicide in agriculture .
Cat. No.: HY-168042
Antibacterial agent 243 is an antibacterial agent, with EC50 values of 0.64 mg/L for Valsa mali, 26 mg/L for allicin, and 0.33 mg/L for tebuconazole. Antibacterial agent 243 can induce hyphal shrinkage and collapse, trigger the accumulation of reactive oxygen species inside cells, regulate antioxidant enzyme activity, initiate lipid peroxidation, and ultimately cause irreversible oxidative damage to Valsa mali cells .
Cat. No.: HY-178051
Target:
Research Areas:
Antifungal agent 135 (Compound C2), an antifungal agent, is a Succinate dehydrogenase (SDH) inhibitor with an IC50 of 1.99 μM. Antifungal agent 135 has potent antifungal activities against Valsa mali, Sclerotinia sclerotiorum and Phytophthora capsici with EC50 s of 0.280, 1.11 and 0.130 mg/L, respectively. Antifungal agent 135 shows protective and curative activities against Phytophthora capsici and Valsa mali by effectively disrupting hyphal structural integrity and inhibiting mycelial growth .
Cat. No.: HY-157018
Antifungal agent 82 (compound G34) is a antifungal agent. Antifungal agent 82 exhibits excellent in vitro antifungal activity against Valsa mali, with an EC50 of 0.57 μg/mL. Antifungal agent 82 also exhibits excellent in vivo protective effects against V. mali at 40 μg/mL .
Cat. No.: HY-163297
CAS No.: 3023095-87-3
Antifungal agent 90 (Compound 7n) is an antifungal agent that inhibits ergosterol biosynthesis. Antifungal agent 90 showed excellent antifungal activity against Valsa mali and Botrytis cinerea with EC50 values respectively. 4.26 and 1.41 μg/mL .
Cat. No.: HY-184730
Target:
Research Areas:
Antifungal agent 171 is a mitochondrial complex III inhibitor with a Botrytis cinerea IC50 of 6.48 mg/L. Antifungal agent 171 interferes with respiratory metabolism by binding to mitochondrial complex III and exhibits broad-spectrum inhibitory activity against Valsa mali, Botrytis cinerea, and Physalospora piricola. Antifungal agent 171 can be used for the research of valsa mali infection, botrytis cinerea infection, physalospora piricola infection .
Cat. No.: HY-176552
Target:
Research Areas:
Tubulin polymerization-IN-83 (Compound A23) is a flavonol derivative. Tubulin polymerization-IN-83 exhibits antifungal activity against various phytopathogenic fungi, with an EC50 of 0.338 μg/mL against Botrytis cinerea. Tubulin polymerization-IN-83 exerts its effects by targeting β-tubulin, disrupting mycelial morphology, and increasing cell membrane permeability, with relatively low ecological and environmental risks .
Cat. No.: HY-183722
Target:
Research Areas:
SDH-IN-46 is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 1.21 μM. SDH-IN-46 disrupts fungal respiration via mitochondrial respiratory chain enzyme targeting and exhibits broad-spectrum antifungal activity. SDH-IN-46 exhibits substantial protective effects against S. sclerotiorum on oilseed rape leaves, Rhizoctonia solani on rice leaves, and Valsa mali on apple fruits .
Cat. No.: HY-184460
CAS No.: 224427-79-6
Category:
Target:
Cat. No.: HY-187516
CAS No.: 3031223-87-4
Antifungal agent 174 is an amide derivative of TPs3, the major photodegradation metabolite of cyprodinil, and also acts as an antifungal agent. Antifungal agent 174 exhibits inhibitory activity against Sclerotinia sclerotiorum. Antifungal agent 174 can be used in studies related to Sclerotinia sclerotiorum infection .
Cat. No.: HY-178196
SDH-IN-32 is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 2.74 μM. SDH-IN-32 exhibits excellent antifungal activity. SDH-IN-32 can destroy the cell membrane structure and increase the permeability of the cell membrane. SDH-IN-32 can decrease the mitochondrial membrane potential (MMP), thereby inducing cell apoptosis and inhibiting the normal growth of mycelia. SDH-IN-32 can be used for the research of infection .
Cat. No.: HY-184388
Target:
Research Areas:
Antifungal agent-168 is an antifungal agent with broad-spectrum inhibitory activity against a variety of pathogenic fungi. Antifungal agent-168 interacts with β-glucan in the cell wall of Botrytis cinerea, disrupting the physiological functions of the cell wall. Antifungal agent-168 damages the hyphal cell membrane, causes electrolyte leakage, and promotes ROS release to accelerate fungal death. Antifungal agent-168 can be used in studies related to Botrytis cinerea infection .
Target:
Research Areas:
Ethyl 2-fluorocinnamate is a substituted ethyl cinnamate derivative with antifungal activity and weak sensitizing activity. Ethyl 2-fluorocinnamate inhibits mycelial growth of phytopathogenic fungi. Ethyl 2-fluorocinnamate can be used in studies related to plant fungal diseases .
Cat. No.: HY-187437
CAS No.: 3133348-60-1
Target:
Research Areas:
CYP51-IN-33 is a CYP51 inhibitor with an IC50 of 0.35 μM against the sterol 14α-demethylase activity of Rhizoctonia solani CYP51. CYP51-IN-33 interferes with CYP51-associated ergosterol biosynthesis, accompanied by changes in hyphal morphology, increased membrane permeability and intracellular ROS accumulation. CYP51-IN-33 can be used in studies on CYP51-targeted antifungal activity and rice sheath blight .
Cat. No.: HY-W558657A
CAS No.: 14990-09-1
Tert-Butyl cinnamate is a tert-butyl cinnamate with antifungal activity and comonomer function, which exhibits an average inhibition rate of 73.0% against phytopathogenic fungi at a concentration of 0.5 mM. Tert-Butyl cinnamate can be used in studies related to phytopathogenic fungal infections .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
