Antifungal agent 174
Antifungal agent 174 is an amide derivative of TPs3, the major photodegradation metabolite of cyprodinil, and also acts as an antifungal agent. Antifungal agent 174 exhibits inhibitory activity against Sclerotinia sclerotiorum. Antifungal agent 174 can be used in studies related to Sclerotinia sclerotiorum infection.
For research use only. We do not sell to patients.
- CAS No.: 3031223-87-4
- Formula: C21H18FN3O
- Molecular Weight:347.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Antifungal agent 174 (compound 7c) potently inhibits mycelial growth of Sclerotinia sclerotiorum with an inhibition rate of 89.6% at 50 μg/mL, while showing weaker activity against Fusarium graminearum (42.7%), Botryosphaeria dothidea (54.6%), and Valsa mali (30.9%)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 3031223-87-4
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Molecular Weight 347.39
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Formula C21H18FN3O
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SMILES
FC1=CC(C(NC2=CC=C(C3=NC(C)=CC(C4CC4)=N3)C=C2)=O)=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antifungal agent 174 Related Classifications
HY-187516 Related Classifications
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