3133348-60-1

CYP51-IN-33 Chemical Structure
3133348-60-1

Chemical Structure

CYP51-IN-33

  • CAS. Nr.: 3133348-60-1
  • Formula:C14H12Cl2N4OS
  • Molecular Weight:355.24

InChIKey: UCDHXCFEWULFKB-UHFFFAOYSA-N

SMILES: OC(C1=NC=C(C)S1)(C2=CC=C(Cl)C=C2Cl)CN3N=CN=C3

Biological Activity:

CYP51-IN-33 is a CYP51 inhibitor with an IC50 of 0.35 μM against the sterol 14α-demethylase activity of Rhizoctonia solani CYP51. CYP51-IN-33 interferes with CYP51-associated ergosterol biosynthesis, accompanied by changes in hyphal morphology, increased membrane permeability and intracellular ROS accumulation. CYP51-IN-33 can be used in studies on CYP51-targeted antifungal activity and rice sheath blight[1].

Art. -Nr. Produktname Reinheit Beschreibung Pricing
HY-187437 		CYP51-IN-33
CYP51-IN-33 is a CYP51 inhibitor with an IC50 of 0.35 μM against the sterol 14α-demethylase activity of Rhizoctonia solani CYP51. CYP51-IN-33 interferes with CYP51-associated ergosterol biosynthesis, accompanied by changes in hyphal morphology, increased membrane permeability and intracellular ROS accumulation. CYP51-IN-33 can be used in studies on CYP51-targeted antifungal activity and rice sheath blight.
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