Antifungal agent-168

Antifungal agent-168 (Compound X7) (5-120 μg/mL; 72 h) exhibits broad-spectrum in vitro antifungal activity against Colletotrichum lagenarium, Valsa mali, Botrytis cinerea, and Fusarium graminearum, with an EC₅₀ of 0.089 μmol/mL against Botrytis cinerea^[1].
Antifungal agent-168 (40 μg/mL; 72 h) disrupts the morphology of Botrytis cinerea mycelium, causing structural damage to cell walls or membranes^[1].
Antifungal agent-168 (5 μg/mL; 24 h) induces oxidative stress in Botrytis cinerea mycelium, promoting the release of reactive oxygen species^[1].
Antifungal agent-168 (0-40 μg/mL; 72 h) primarily interacts with β-glucan in the cell wall of Botrytis cinerea in a concentration-dependent manner, disrupting normal cell wall physiological functions^[1].
Antifungal agent-168 (10-40 μg/mL; 0.5-24 h) damages the cell membranes of Botrytis cinerea mycelium in a dose- and time-dependent manner, leading to electrolyte leakage and increased relative conductivity^[1].
Antifungal agent-168 (2-32 μg/mL) exhibits low in vitro cytotoxicity to HEK-293T cells, with >80% cell survival at concentrations up to 16 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.