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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
WT1
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "WT1" in MCE Product Catalog:
7
7 Publications Verification
Synonyms: NP031112
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Tideglusib (NP031112) is an irreversible GSK-3 inhibitor with IC50s of 5 nM and 60 nM for GSK-3β WT (1 h preincubation) and GSK-3β C199A (1 h preincubation), respectively.
4
4 Cited Publications
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IDH-305 is an orally available, mutant-selective and brain-penetrant IDH1 inhibitor that targets IDH1 (R132) mutation. IDH-305 exhibits greater than 200 fold selectivity for mutant IDH1 isoforms vs. WT (IC50= 27 nM (IDH1 R132H), 28 nM (IDH1 R132C), 6.14 µM (IDH1 WT)) .
1
1 Cited Publications
Borussertib, a chemical probe, is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt, with an IC50 of 0.8 nM and a Ki of 2.2 nM for Akt wt .
Cat. No.: HY-P99650
CAS No.: 2367001-70-3
Synonyms: WT1
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Cat. No.: HY-RS17032
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Wt1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Wt1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P11084
CAS No.: 256952-63-3
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Cat. No.: HY-W143698
CAS No.: 404844-11-7
PDGFRα kinase inhibitor 2 (compound 1), an Imatinib (HY-15463) analogue, is a covalent and irreversible kinase inhibitor with IC50s of 6.95 μM, 2.45 μM, 1.39 μM for ABL1 wt, KIT wt, PDGFRR wt .
Cat. No.: HY-RS15853
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WT1 Human Pre-designed siRNA Set A contains three designed siRNAs for WT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P11084A
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Cat. No.: HY-P3058
CAS No.: 852243-39-1
Synonyms: WT-1 A1
Cat. No.: HY-RS23476
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Wt1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Wt1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P4145
CAS No.: 935395-33-8
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Cat. No.: HY-120765
CAS No.: 1304750-47-7
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BRD2879 is a potent IDH1-R132H inhibitor with IC50 values of 0.05, 2.5, >20, >20 µM for IDH1-R132H, IDH1-R132C, IDH1-WT, IDH2-R140Q, respectively. BRD2879 reduces (R)-2-hydroxyglutarate (R-2HG) levels [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
