1800070-77-2
1800070-77-2
Chemical Structure
Borussertib
- CAS No.: 1800070-77-2
- Formula:C36H32N6O3
- Molecular Weight:596.68
IUPAC Name: N-(2-oxo-3-(1-(4-(5-oxo-3-phenyl-5,6-dihydro-1,6-naphthyridin-2-yl)benzyl)piperidin-4-yl)-2,3-dihydro-1H-benzo[d]imidazol-5-yl)acrylamide
InChIKey: HXBRBOYWXDLHDC-UHFFFAOYSA-N
SMILES: C=CC(NC1=CC=C(N2)C(N(C3CCN(CC4=CC=C(C5=NC6=C(C(NC=C6)=O)C=C5C7=CC=CC=C7)C=C4)CC3)C2=O)=C1)=O
Biological Activity: Borussertib, a chemical probe, is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt, with an IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Borussertib | 99.18% | Borussertib, a chemical probe, is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt, with an IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt. | ||||||||||||||||||||
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References
Keywords
