1 Result for "

Wee1/HDAC-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Wee1/HDAC-IN-1" in MCE Product Catalog:

Cat. No.: HY-179272
CAS No.: 3037071-29-4
Target:  

Wee1 HDAC Apoptosis

Research Areas:  

Cancer

Wee1/HDAC-IN-1 is a dual Wee1/HDAC inhibitor with an IC50 of 1.2 nM for Wee1 and IC50 values of 196 nM for HDAC1, 156 nM for HDAC3, and 55 nM for HDAC6. Wee1/HDAC-IN-1 exhibits strong antiproliferative activity against MV4-11 cells with an IC50 of 0.076 μM. Wee1/HDAC-IN-1 selectively binds to Wee1 and HDACs. Wee1/HDAC-IN-1 interferes with DNA damage repair pathways and induces apoptosis in MV4-11 cells. Wee1/HDAC-IN-1 Wee1/HDAC-IN-1 can be used for the research of acute myeloid leukemia (AML) [1].
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