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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
YB-1
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "YB-1" in MCE Product Catalog:
5
5 Cited Publications
Cat. No.: HY-19713
CAS No.: 1627709-94-7
Target:
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LJI308 is a potent pan-ribosomal S6 kinase (RSK) inhibitor, with IC50s of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. LJI308 inhibits the phosphorylation of RSK (T359/S363) and YB-1 (S102) after irradiation, treatment with EGF, and in cells expressing a KRAS mutation [1] .
2
2 Cited Publications
SU056 is a YB-1 inhibitor. SU056 induces cell-cycle arrest, apoptosis, and inhibits cell migration in ovarian cancer cells. SU056 interacts with YB-1 and inhibits and its associated downstream proteins and pathways. SU056 can enhance the cytotoxic effects of Paclitaxel (HY-B0015) [1].
2
2 Cited Publications
Research Areas:
CAY10526 is an inhibitor of Y-box binding protein 1 (YB-1) and microsomal prostaglandin E2 synthase 1 (mPGES1). CAY10526 inhibits the production of PGE2 by suppressing YB-1 and mPGES1. CAY10526 induces cell apoptosis (apoptosis) and inhibits the JAK/STAT, TGF-β/Smad3 and PI3K/AKT signaling pathways. CAY10526 can be used in research related to melanoma, prostate cancer, esophageal adenocarcinoma, T-cell lymphoma, etc [1] .
1
1 Cited Publications
Cat. No.: HY-P704205
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: YBX1; Y‑Box Binding Protein 1; NSEP1; YB‑1; DBPB; YB1; MDR‑NF1; NSEP‑1; CSDA2; BP‑8; CSDB; CCAAT‑Binding Transcription Factor I Subunit A; Nuclease‑Sensitive Element‑Binding Protein 1; Enhancer Factor I Subunit A; Y‑Box Transcription Factor; Y‑Box‑Binding
1
1 Cited Publications
Cat. No.: HY-P80936
Synonyms: YBX1; NSEP1; YB1; Nuclease-sensitive element-binding protein 1; CCAAT-binding transcription factor I subunit A; CBF-A; DNA-binding protein B; DBPB; Enhancer factor I subunit A; EFI-A; Y-box transcription factor; Y-box-binding protein 1; YB-
Category:
Triterpenes Leguminosae Terpenoids Plants Disease Research Fields Inflammation/Immunology Glycine soja Sieb. Et Zucc.
Target:
Cat. No.: HY-RS15916
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YBX1 Human Pre-designed siRNA Set A contains three designed siRNAs for YBX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-144434
CAS No.: 2761698-77-3
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RSK-IN-1 (compound 7d) is a RSK inhibitor that inhibits the YB-1 phosphorylation. RSK-IN-1 has anti-tumor effects [1].
Cat. No.: HY-P990826
Cat. No.: HY-175206
CAS No.: 2761881-65-4
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Research Areas:
P-gp-IN-30 (Compound 13) is a P-glycoprotein (P-gp) inhibitor by targeting YB-1. P-gp-IN-30 significantly enhances sensitivity to Paclitaxel by reducing total YB-1 and nucleus YB-1 protein expression, inhibiting the expression and function of downstream P-gp, further suppressing the efflux rate of Paclitaxel. P-gp-IN-30 potently inhibits tumor growth in A549/Taxol xenografts mice model with combination of Paclitaxel (HY-B0015). P-gp-IN-30 can be used for non-small cell lung cancer (NSCLC) research [1].
Cat. No.: HY-RS23592
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Research Areas:
Ybx1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ybx1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P80375
Synonyms: NSEP1, YB1, YBX1, Y-box-binding protein 1, YB-1, CCAAT-binding transcription factor I subunit A, DNA-binding protein B, Enhancer factor I subunit A, Nuclease-sensitive element-binding protein 1, Y-box transcription factor, CBF-A, DBPB, EFI-A
Cat. No.: HY-P87886
Synonyms: NSEP1, YB1, YBX1, Y-box-binding protein 1, YB-1, CCAAT-binding transcription factor I subunit A, DNA-binding protein B, Enhancer factor I subunit A, Nuclease-sensitive element-binding protein 1, Y-box transcription factor, CBF-A, DBPB, EFI-A
Cat. No.: HY-P702822
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: YBX1; Y‑Box Binding Protein 1; NSEP1; YB‑1; DBPB; YB1; MDR‑NF1; NSEP‑1; CSDA2; BP‑8; CSDB; CCAAT‑Binding Transcription Factor I Subunit A; Nuclease‑Sensitive Element‑Binding Protein 1; Enhancer Factor I Subunit A; Y‑Box Transcription Factor; Y‑Box‑Binding Protein 1; DNA‑
Species:
Source:
Cat. No.: HY-RS16252
Target:
Research Areas:
Ybx1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ybx1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
