3 Results for "

alpha-mannosidosis

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "alpha-mannosidosis" in MCE Product Catalog:

Cat. No.: HY-P2950
CAS No.: 9025-42-7
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

α-Mannosidase is a hydrolytic enzyme targeting mannose-containing glycoproteins or glycolipids. α-Mannosidase is promising for research of inherited α-mannosidosis .
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Cat. No.: HY-E70185
Synonyms: EC:3.2.1.24; MAN2B1; LAMAN
Lysosomal α-mannosidase (EC:3.2.1.24) is a low pH-activated exoglycosidase that hydrolyzes α-mannosidic linkages on mannan and N-linked oligosaccharides, and its activation requires Zn 2+. As the major exoglycosidase in the glycoprotein degradation pathway, lysosomal α-mannosidase cleaves α1,2-, α1,3- and α1,6-mannosidic linkages during a non-random, ordered degradation process to generate Man1GlcNAc1-2 for further lysosomal processing. Lysosomal α-mannosidase can be used in studies related to α-mannosidosis .
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Cat. No.: HY-181175
CAS No.: 1531606-19-5
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

OMJ-4 is a mutant alpha-mannosidase modulator. OMJ-4 can restore mutant alpha-mannosidase's catalytic function, and induces changes in compactness and active-site flexibility to improve substrate accommodation. OMJ-4 acts as an inducer of substrate reactivity, increasing the reactivity of mannose disaccharide bound to mutant alpha-mannosidase. OMJ-4 reduces the activation energy required for the enzymatic reaction of mutant alpha-mannosidase. OMJ-4 can be used for the research of alpha-mannosidosis .
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