44 Results for "

amino terminus

" in MedChemExpress (MCE) Product Catalog:
Products (44)

44 Results for "amino terminus" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-P1136
CAS No.: 1507930-57-5
Target:  

Gap Junction Protein

Research Areas:  

Cardiovascular Disease

Gap19, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 inhibits hemichannels caused by preventing intramolecular interactions of the C-terminus (CT) with the CL. Gap19 is not blocking GJ channels or Cx40/pannexin-1 hemichannels. Gap19 has protective effects against myocardial .
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5
5 Cited Publications
Cat. No.: HY-P1136A
Target:  

Gap Junction Protein

Research Areas:  

Cardiovascular Disease

Gap19 TFA, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 TFA inhibits hemichannels caused by preventing intramolecular interactions of the C-terminus (CT) with the CL. Gap19 TFA is not blocking GJ channels or Cx40/pannexin-1 hemichannels. Gap19 TFA has protective effects against myocardial .
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2
2 Cited Publications
Cat. No.: HY-P3815
CAS No.: 132176-35-3
Target:  

Casein Kinase

Research Areas:  

Others

Casein Kinase 2 Substrate Peptide is a common CK2 substrate peptide. Casein Kinase 2 Substrate Peptide is synthesized with its C-terminus conjugated to 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid (EDANS). Casein Kinase 2 Substrate Peptide can be used for protein kinase CK2 activity determination .
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1
1 Cited Publications
Cat. No.: HY-P2543
CAS No.: 150138-78-6
Neuropeptide Y (3-36) (human, rat) is a neuropeptide Y fragment derived from humans or rats. Neuropeptide Y is an extremely abundant neurotransmitter in central and peripheral neurons, and it participates in the regulation of psychomotor activity, circadian rhythm, feeding behavior and cardiovascular function. Neuropeptide Y (3-36) (human, rat) can serve as a substrate to be sequentially degraded from its N-terminus by AfuS28, and it requires binding to AfuS28 and SedB to be decomposed into amino acids, dipeptides and tripeptides [1] [2].
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Cat. No.: HY-133513
CAS No.: 1919794-40-3
Purity:  98.15%
Synonyms: (±)-H3L28
Target:  

Drug Derivative

Research Areas:  

Cancer

(±)-H3RESCA-TFP ((±)-H3L28) is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA). (±)-H3RESCA-TFP can be used to conjugate the chelator with a biomolecule via amine coupling (e.g., N terminus and/or the ε-amino groups of lysine) .
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Cat. No.: HY-P1732
CAS No.: 203716-10-3
Research Areas:  

Cancer

Transportan is an amphipathic cell-penetrating peptide containing 12 functional amino acids from the amino terminus of the neuropeptide galanin and mastoparan in the carboxyl terminus, connected via a lysine. Transportan interacts with galanin receptors and G-proteins, modulates GTPase activity, enters cells via direct translocation and endocytic pathways, accumulates in cytoplasmic, nuclear, and membranous structures, and delivers cargo including peptides, PNAs, proteins, siRNA, and liposomes [12].
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Cat. No.: HY-P10531
CAS No.: 2413353-86-1
Target:  

Peptides

Research Areas:  

Others

ALFA-tag is a small and stable α-helical structure composed of 15 amino acids. ALFA-tag is highly hydrophilic and can be placed at the N-terminus, C-terminus, or between two independently folded domains of the target protein without affecting the function of the protein. ALFA-tag is widely used as an epitope tag and is used for the detection and manipulation of proteins in living cells .
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Cat. No.: HY-P99163
CAS No.: 2096513-89-0
Synonyms: ABBV-8E12; C2N-8E12

Target:  

Tau Protein

Research Areas:  

Neurological Disease

Tilavonemab (ABBV-8E12) is a humanized anti-tau monoclonal antibody that binds to amino acids 25-30 near the N-terminus of the tau protein. Tilavonemab can block the ability of human and mouse neurons to uptake tau aggregates. Tilavonemab can be used for research on Alzheimer’s disease and other tauopathies .
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Cat. No.: HY-125372
CAS No.: 16348-49-5
Purity:  99.85%
Synonyms: ABAO
Research Areas:  

Others

2-Amino benzamidoxime (ABAO) acts as a bioconjugation reagent precursor and a fluorescent probe precursor. 2-Amino benzamidoxime contains an aniline group for imine activation of aldehydes, as well as a nucleophilic group (Nu:) located at the ortho position of the amine, which is responsible for intramolecular cyclization. 2-Amino benzamidoxime reacts with glyoxal at the N-terminus of phage-displayed peptide libraries. Derivatives of 2-Amino benzamidoxime can be used for protein bioconjugation. Derivatives of 2-Amino benzamidoxime serve as fluorescent probes .\n



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Cat. No.: HY-P1565
CAS No.: 888486-23-5
Synonyms: TD 1 Disulfide(peptide)
Target:  

Na+/K+ ATPase

Research Areas:  

Inflammation/Immunology

Transdermal Peptide Disulfide (TD 1 Disulfide(peptide)) is a 11-amino acid peptide, binds toNa +/K +-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide Disulfide can enhance the transdermal delivery of many macromolecules .
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Cat. No.: HY-P1565A
Synonyms: TD 1 Disulfide(peptide) TFA
Target:  

Na+/K+ ATPase

Research Areas:  

Others

Transdermal Peptide Disulfide TFA (TD 1 Disulfide(peptide) TFA) is a 11-amino acid peptide, binds to Na +/K +-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide Disulfide TFA can enhance the transdermal delivery of many macromolecules .
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Cat. No.: HY-34738
CAS No.: 58885-58-8
Synonyms: 3-(Boc-amino)-1-propanol
Research Areas:  

Others

Boc-β-Ala-ol (3-(Boc-amino)-1-propanol) is an alanine derivative with a Boc protecting group at the N-terminus, which can be used to synthesize bioactive peptide mimics, such as Nα-Benzoyl-α-azaornithine phenyl ester, which has trypsin inhibitory activity .
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Cat. No.: HY-136881
CAS No.: 954371-52-9
Target:  

CCR

Research Areas:  

Inflammation/Immunology

CH0076989 is a specific CCR3 agonist. CH0076989 activates eosinophils and transfectants expressing both wild-type CCR3 and a CCR1:CCR3 chimaeric receptor lacking the CCR3 amino-terminus. CH0076989 has a direct interaction with the transmembrane helices of CCR3, supported by the complete loss of its activity due to mutations of the residues Y41, Y113 and E287. CH0076989 can be used for the study of inflammation and allergic diseases (such as asthma) .
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Cat. No.: HY-131800
CAS No.: 4209-30-7
Target:  

ATP Synthase

Research Areas:  

Metabolic Disease

3'-NH2-ATP, an ATP analogue, is a potent and competitive inhibitor of ATP, with a Ki of 2.3 μM. 3'-NH2-ATP can be used to synthesis of 3′-Amino-3′-deoxy transfer RNA by incorporation into the 3' terminus of tRNA-C-C .
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Cat. No.: HY-P3971
CAS No.: 162559-45-7
Target:  

TGF-beta/Smad

Research Areas:  

Inflammation/Immunology

H-Leu-Ser-Lys-Leu-OH (LSYL) is a latency-associated peptide at the amino terminus of LAP, with inhibitory effect on TGF-β1 activation. H-Leu-Ser-Lys-Leu-OH, binding with KRFK (HY-P3970), can block the signal transduction of TGF-β1, and prevent the progression of hepatic damage and fibrosis .
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Cat. No.: HY-P5429
CAS No.: 146064-85-9
Target:  

Peptides

Research Areas:  

Others

DNA-PK Substrate is a biological active peptide. (A substrate for DNA-dependent protein kinase (DNA-PK), phosphorylation. DNA-PK is essential for the repair of DNA double-strand breaks. This peptide corresponding to 11–24 amino acids of human p53 with threonine 18 and serine 20 changed to alanine is used as a substrate for the assay of DNA-PK activityPyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)
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Cat. No.: HY-P2842
CAS No.: 9031-94-1
Research Areas:  

Others Cancer

Aminopeptidase catalyzes the cleavage of amino acids from the amino terminus of protein or peptide substrates .
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Cat. No.: HY-P1493
CAS No.: 36204-23-6
Synonyms: FPB,human
Target:  

Thrombin

Research Areas:  

Inflammation/Immunology

Fibrinopeptide B, human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin.
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Cat. No.: HY-P4807
CAS No.: 122071-54-9
Synonyms: Hez-PBAN
Target:  

Peptides

Research Areas:  

Neurological Disease

Pheromone Biosynthesis Activating Neuropeptide (Helicoverpa assulta, Heliothis zea) (PBAN), a member of the PBAN/Pyrokinin neuropeptide family, characterized by a common amino acid sequence FXPRLamide motif in the C-terminus .
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Cat. No.: HY-138311
Research Areas:  

Cancer

Boc-NH-PEG10000-Thiol is a PEG derivative containing Boc and thiol groups. After acidic deprotection of the Boc terminus, a free amino group is exposed, and the thiol terminus can efficiently couple with various groups, making it suitable for research in ADC drug synthesis, hydrogel construction, and nanoparticle delivery.
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