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(±)-H3RESCA-TFP (Synonyms: (±)-H3L28)

Cat. No.: HY-133513
Handling Instructions

(±)-H3RESCA-TFP ((±)-H3L28) is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA). (±)-H3RESCA-TFP can be used to conjugate the chelator with a biomolecule via amine coupling (e.g., N terminus and/or the ε-amino groups of lysine).

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(±)-H3RESCA-TFP Chemical Structure

(±)-H3RESCA-TFP Chemical Structure

CAS No. : 1919794-40-3

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Description

(±)-H3RESCA-TFP ((±)-H3L28) is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA). (±)-H3RESCA-TFP can be used to conjugate the chelator with a biomolecule via amine coupling (e.g., N terminus and/or the ε-amino groups of lysine)[1].

In Vitro

The aluminum fluoride restrained complexing agent (Al18F-RESCA) method combines the chemical advantages of a chelator-based radiolabeling method with the unique physical properties of the radionuclide of choice, fluorine-18. Proteins of interest can be conjugated to RESCA via amine coupling using (±)-H3RESCA-TFP. Al18F-labeled proteins can be obtained with moderate (12-17 GBq/µmol) to good (80-85 GBq/µmol) apparent molar activity, depending on the starting activity of 18F-[1].

Molecular Weight

584.51

Formula

C₂₇H₂₈F₄N₂O₈

CAS No.

1919794-40-3

SMILES

O=C(CC1=CC=C(CN(CC(O)=O)[[email protected]@H]2CCCC[[email protected]]2N(CC(O)=O)CC(O)=O)C=C1)OC3=C(F)C(F)=CC(F)=C3F

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

(±)-H3RESCA-TFP(±)-H3L28OthersRESCAtetrafluorophenylε-aminolysinchelatorbiomoleculeamineInhibitorinhibitorinhibit

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