H-Leu-Ser-Lys-Leu-OH
H-Leu-Ser-Lys-Leu-OH (LSYL) is a latency-associated peptide at the amino terminus of LAP, with inhibitory effect on TGF-β1 activation. H-Leu-Ser-Lys-Leu-OH, binding with KRFK (HY-P3970), can block the signal transduction of TGF-β1, and prevent the progression of hepatic damage and fibrosis.
For research use only. We do not sell to patients.
- CAS No.: 162559-45-7
- Formula: C21H41N5O6
- Molecular Weight:459.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
TGF-β1[1]
H-Leu-Ser-Lys-Leu-OH (LSKL) also blocks the activation of TGF-b1 by TSP-1, and decreases the activation of TGF-b1 by the KRFK peptide[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 162559-45-7
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Molecular Weight 459.58
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Formula C21H41N5O6
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Sequence Shortening
LSKL
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
H-Leu-Ser-Lys-Leu-OH Related Classifications
HY-P3971 Related Classifications
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