3'-NH2-ATP
3'-NH2-ATP, an ATP analogue, is a potent and competitive inhibitor of ATP, with a Ki of 2.3 μM. 3'-NH2-ATP can be used to synthesis of 3′-Amino-3′-deoxy transfer RNA by incorporation into the 3' terminus of tRNA-C-C.
For research use only. We do not sell to patients.
- CAS No.: 4209-30-7
- Formula: C10H17N6O12P3
- Molecular Weight:506.20
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
3'-Deoxy-3'-amino-ATP can be used as a substrate to synthesis of 3′-Amino-3′-deoxy transfer RNA[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 4209-30-7
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Molecular Weight 506.20
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Formula C10H17N6O12P3
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SMILES
NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](N)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Armstrong VW, et, al. Interaction of substrate analogues with Escherichia coli DNA-dependent RNA polymerase. Eur J Biochem. 1976 Nov 1;70(1):33-8. [Content Brief]
[2]. Fraser TH, et, al. Synthesis and aminoacylation of 3'-amino-3'-deoxy transfer RNA and its activity in ribosomal protein synthesis. Proc Natl Acad Sci U S A. 1973 Sep;70(9):2671-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3'-NH2-ATP Related Classifications
HY-131800 Related Classifications
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