Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
antipsoriatic
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "antipsoriatic" in MCE Product Catalog:
4
Target:
Category:
Alkaloids Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth. Disease Research Fields Inflammation/Immunology Indole Alkaloids
Target:
Target:
Research Areas:
Dithranol (Anthralin) is an anthraquinone derivative, with potent anti-psoriatic effects. Dithranol can inhibit DNA replication and repair .
Category:
Synonyms: Ro 13-6298; Arotinoid ethyl ester
Target:
Research Areas:
Arotinoid (RO 13-6298) is a retinoid, and acts as an orally active and highly potent agonist of retinoic acid receptors (RARs) with antipsoriatic effects. Arotinoid has antipapiltoma activity with an ED50 of 0.05 mg/kg. Arotinoid can be used for the research of skin carcinomas .
Cat. No.: HY-106480
CAS No.: 75464-11-8
Target:
Research Areas:
Butantrone is a derivative of Dithranol (HY-B0738) with antipsoriatic activity .
Cat. No.: HY-162599
Category:
Natural Products Apiaceae Hypericaceae Hypericum patulum Thunb. Plants Heracleum sibiricum L.
Target:
Cat. No.: HY-121256
CAS No.: 18921-73-8
Research Areas:
Chlorasquin inhibits thymidylate synthetase with an approximate Ki value of 4.9 μM. Chlorasquin is also a folate antagonist, testing the Methotrexate (HY-14519) effect. Chlorasquin binds tighter to dihydrofolate reductase at alkaline pH than does Methotrexate, which is promising for research of antipsoriatic agents .
Cat. No.: HY-19380
CAS No.: 241151-12-2
Target:
Research Areas:
Ro-65-2299 is an orally active retiferol Vitamin D analogue and a potential VDR agonist (ED50 = 180 nM). Ro-65-2299 can induce thickening of the epidermis and exhibits antipsoriatic effect in hairless mice (ED50 = 7.5 mg/kg). Ro-65-2299 can be used for the researches of inflammation and immunology, such as psoriasis .
Cat. No.: HY-155243
CAS No.: 857758-13-5
Target:
Research Areas:
12R-LOX-IN-1 (Compound 4a) is a 12R-LOX inhibitor (IC50: 28.25 μM). 12R-LOX-IN-1 inhibits the hyper-proliferative state and colony forming potential of Imiquimod (HY-B0180)-induced psoriatic keratinocytes. 12R-LOX-IN-1 inhibits reactive oxygen species, Ki67, IL-17A, TNF-α and IL-6 production. 12R-LOX-IN-1 can be used for antipsoriatic research .
Cat. No.: HY-19911
CAS No.: 381212-03-9
Synonyms: SMD-502
Target:
Research Areas:
Pefcalcitol is a new antipsoriatic anteagent candidates having 16-en-22-oxa-vitamin D3 structures.
Cat. No.: HY-169007
Target:
Research Areas:
STAT3-IN-34 (Compound 15E) is an inhibitor for STAT3, and inhibits the nuclear translocation and transcriptional regulator activity of STAT3. STAT3-IN-34 inhibits the proliferation of cell HaCaT with IC50 of 0.008 μM. STAT3-IN-34 inhibits IL-17A expression and ameliorates Imiquimod (HY-B0180)-induced psoriasis in mice .
Target:
Research Areas:
Dithranol (Standard) is the analytical standard of Dithranol. This product is intended for research and analytical applications. Dithranol (Anthralin) is an anthraquinone derivative, with potent anti-psoriatic effects. Dithranol can inhibit DNA replication and repair .
Cat. No.: HY-161864
CAS No.: 2256751-16-1
Target:
Research Areas:
STAT3-IN-29 (Compound B20) is an inhibitor for STAT3. STAT3-IN-29 inhibits the proliferation of HaCaT cell with IC50 of 0.09 µM, ameliorates the IMQ-induced psoriasis in mouse models .
Cat. No.: HY-124099
CAS No.: 110545-79-4
Target:
Research Areas:
SCH 40120 is a potent leukotriene inhibitor with antiinflammatory effects. SCH 40120 suppresses T cell proliferative responses, antigen-specific and poly-clonally-induced in vitro antibody responses. SCH 40120 suppresses an edematous response and inhibits the recruitment of circulating neutrophils into sites of inflammation. SCH 40120 is proming for rasearch of anti-psoriatic agents .
Cat. No.: HY-168212
Research Areas:
PDE4-IN-22 (Compound 2e) is a PDE4 inhibitor with an IC50 value of 2.4 nM. PDE4-IN-22 exhibits anti-inflammatory activity and demonstrates significant anti-psoriatic effects in an Imiquimod (HY-B0180)-induced psoriasis mouse model .
Category:
Alkaloids Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth. Indole Alkaloids
Target:
Cat. No.: HY-106735R
CAS No.: 71441-09-3
Synonyms: Ro 13-6298 (Standard); Arotinoid ethyl ester (Standard)
Target:
Research Areas:
Arotinoid (Standard) (Ro 13-6298 (Standard)) is the analytical standard of Arotinoid (HY-106735). This product is intended for research and analytical applications. Arotinoid (RO 13-6298) is a retinoid, and acts as an orally active and highly potent agonist of retinoic acid receptors (RARs) with antipsoriatic effects. Arotinoid has antipapiltoma activity with an ED50 of 0.05 mg/kg. Arotinoid can be used for the research of sKin carcinomas .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
