1143-38-0
1143-38-0
Chemical Structure
Dithranol
Synonym(s): Anthralin
- CAS No.: 1143-38-0
- Formula:C14H10O3
- Molecular Weight:226.23
IUPAC Name: 1,8-dihydroxyanthracen-9(10H)-one
InChIKey: NUZWLKWWNNJHPT-UHFFFAOYSA-N
SMILES: O=C1C2=C(C=CC=C2O)CC3=CC=CC(O)=C13
Biological Activity: Dithranol (Anthralin) is an anthraquinone derivative, with potent anti-psoriatic effects. Dithranol can inhibit DNA replication and repair[1][2].
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Dithranol | 95.26% | Dithranol (Anthralin) is an anthraquinone derivative, with potent anti-psoriatic effects. Dithranol can inhibit DNA replication and repair. | ||||||||||||||||||||
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Dithranol (Standard) | ≥98% | Dithranol (Standard) is the analytical standard of Dithranol. This product is intended for research and analytical applications. Dithranol (Anthralin) is an anthraquinone derivative, with potent anti-psoriatic effects. Dithranol can inhibit DNA replication and repair. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.81
HY-B0923Danthron -
Similarity Score 0.80
HY-W008764Anthrarufin -
Similarity Score 0.76
HY-D0226RQuinizarin (Standard) -
Similarity Score 0.75
HY-W0008381-Hydroxyanthraquinone -
Similarity Score 0.72
HY-N9362REmodinanthrone (Standard) -
Similarity Score 0.72
HY-13595Chrysophanol -
Similarity Score 0.71
HY-N0563Alizarin -
Similarity Score 0.71
HY-N78506PGD-IN-1 -
Similarity Score 0.70
HY-124833Quinalizarin -
Explore the MedChemAI to find more analogs
References
- [1]. L Kemény , et al. Dithranol: a review of the mechanism of action in the treatment of psoriasis vulgaris. Skin Pharmacol. 1990;3(1):1-20. [Content Brief]
- [2]. J M Clark, et al. Inhibition of DNA replication and repair by anthralin or danthron in cultured human cells. J Invest Dermatol. 1982 Jul;79(1):18-22. [Content Brief]
