1-Hydroxyanthraquinone
Based on 1 Customer Validation
1-Hydroxyanthraquinone, a naturally occurring compound with oral activity from some plants like Tabebuia avellanedae, exhibits carcinogenic effect.
For research use only. We do not sell to patients.
- Purity: 99.52%
- CAS No.: 129-43-1
- Formula: C14H8O3
- Molecular Weight:224.21
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All DNA/RNA Synthesis Isoforms
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Thirty rats[1].
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Dosage:1% HA in diet.
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Administration:Diet.
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Result:Associated with decreased weight gain which was particularly marked towards the termination of experiment.
One of the 30 rats in group 1 (experimental group) died of pneumonia 243 days after the start of experiment.
A second rat died in an unnourished state at day 280, demonstrating a large tumor in the colon.
Seven animals of the group died spontaneously or were sacrificed upon becoming moribund between 335 and 462 days.
A total of 21 rats of group 1 survived until the end of experiment (mean value of total intake of HA/rat was 76.8 g).
Chemical Information
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CAS No. 129-43-1
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Appearance Solid
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Molecular Weight 224.21
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Formula C14H8O3
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Color Yellow to orange
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SMILES
O=C(C1=C2C=CC=C1)C3=CC=CC(O)=C3C2=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 16.67 mg/mL (74.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4601 mL | 22.3005 mL | 44.6010 mL | 111.5026 mL |
| 5 mM | 0.8920 mL | 4.4601 mL | 8.9202 mL | 22.3005 mL | |
| 10 mM | 0.4460 mL | 2.2301 mL | 4.4601 mL | 11.1503 mL | |
| 15 mM | 0.2973 mL | 1.4867 mL | 2.9734 mL | 7.4335 mL | |
| 20 mM | 0.2230 mL | 1.1150 mL | 2.2301 mL | 5.5751 mL | |
| 25 mM | 0.1784 mL | 0.8920 mL | 1.7840 mL | 4.4601 mL | |
| 30 mM | 0.1487 mL | 0.7434 mL | 1.4867 mL | 3.7168 mL | |
| 40 mM | 0.1115 mL | 0.5575 mL | 1.1150 mL | 2.7876 mL | |
| 50 mM | 0.0892 mL | 0.4460 mL | 0.8920 mL | 2.2301 mL | |
| 60 mM | 0.0743 mL | 0.3717 mL | 0.7434 mL | 1.8584 mL |