PDE4-IN-22
PDE4-IN-22 (Compound 2e) is a PDE4 inhibitor with an IC50 value of 2.4 nM. PDE4-IN-22 exhibits anti-inflammatory activity and demonstrates significant anti-psoriatic effects in an Imiquimod (HY-B0180)-induced psoriasis mouse model.
For research use only. We do not sell to patients.
- Formula: C22H19F4N3O3
- Molecular Weight:449.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 2.4 nM (PDE4)[1].
Chemical Information
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Molecular Weight 449.40
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Formula C22H19F4N3O3
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SMILES
O=C(C1=CNC(C2=CC=C(OC(F)F)C(OCC3CC3)=C2)=N1)NCC4=CC(F)=CC=C4F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PDE4-IN-22 Related Classifications
HY-168212 Related Classifications
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