PDE4-IN-22
PDE4-IN-22 (Compound 2e) is a PDE4 inhibitor with an IC50 value of 2.4 nM. PDE4-IN-22 exhibits anti-inflammatory activity and demonstrates significant anti-psoriatic effects in an Imiquimod (HY-B0180)-induced psoriasis mouse model.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C22H19F4N3O3
- Peso molecular:449.40
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
IC50: 2.4 nM (PDE4)[1].
Chemical Information
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Peso molecular 449.40
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Fòrmula C22H19F4N3O3
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SMILES
O=C(C1=CNC(C2=CC=C(OC(F)F)C(OCC3CC3)=C2)=N1)NCC4=CC(F)=CC=C4F
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)