STAT3-IN-34
STAT3-IN-34 (Compound 15E) is an inhibitor for STAT3, and inhibits the nuclear translocation and transcriptional regulator activity of STAT3. STAT3-IN-34 inhibits the proliferation of cell HaCaT with IC50 of 0.008 μM. STAT3-IN-34 inhibits IL-17A expression and ameliorates Imiquimod (HY-B0180)-induced psoriasis in mice.
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- Formel: C19H16N2O4S
- Molecular Weight:368.41
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HaCaT | IC50 |
0.008 μM
Compound: 15e
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Antiproliferative activity against human HaCaT cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HaCaT cells incubated for 48 hrs by MTT assay
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[PMID: 39151117] |
Chemical Information
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Molecular Weight 368.41
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Formel C19H16N2O4S
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SMILES
CN(CCOC1=CC=C(C=C1)C2=NOC3=C2C(C4=C(C3=O)C=CS4)=O)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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