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Results for "

axenic

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Peptides

2

Natural
Products

Cat. No. Nombre del producto Target Áreas de investigación Chemical Structure
  • HY-B0217
    Nitazoxanide
    10+ Cited Publications

    NTZ; NSC 697855

    		 Parasite Influenza Virus Autophagy Infection Cancer
    Nitazoxanide (NTZ), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC50 of 2.4 μM . Nitazoxanide can be used for the research of parasitic gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model .
    Nitazoxanide
  • HY-162066
    DNDI-6174

    		Parasite Infection
    DNDI-6174 is an orally active Leishmania cytochrome b (Qi site of cytochrome bc1 complex/complex III) inhibitor. DNDI-6174 binds to the Qi site of Leishmania cytochrome b, inhibits cytochrome bc1 complex activity in the parasite's electron transport chain across promastigote and axenic amastigote stages. DNDI-6174 reduces parasite burden in rodent models, inhibits growth of various Leishmania species, drug-resistant clinical isolates, and Trypanosoma cruzi, with marginal activity against Trypanosoma brucei. DNDI-6174 can be used for the research of visceral leishmaniasis, cutaneous leishmaniasis .
    DNDI-6174
  • HY-P11337
    Scyptolin B

    		Endogenous Metabolite Elastase Others
    Scyptolin B, a cyclic depsipeptides, is a secondary metabolite. Scyptolin B can be isolated from axenic cultures of Scytonema hofmanni PCC 7110. Scyptolin B selective inhibits porcine pancreatic Elastase with an IC50 of 3.1 μg/mL .
    Scyptolin B
  • HY-B0217R
    Nitazoxanide (Standard)

    NTZ (Standard); NSC 697855 (Standard)

    		 Reference Standards Parasite Influenza Virus Autophagy Infection Cancer
    Nitazoxanide (Standard) is the analytical standard of Nitazoxanide. This product is intended for research and analytical applications. Nitazoxanide (NTZ), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC50 of 2.4 μM . Nitazoxanide can be used for the research of parasitic gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model .
    Nitazoxanide (Standard)
  • HY-151151
    Trypanothione synthetase-IN-3

    		Parasite Infection
    Trypanothione synthetase-IN-3 is a noncompetitive mixed hyperbolic Trypanothione synthetase (TryS) inhibitor (Ki: 0.8 μM). Trypanothione synthetase-IN-3 can be used in the study of parasites, such as L. infantum .
    Trypanothione synthetase-IN-3
  • HY-N17223
    1,2-Di-O-linolenoylglycerol 3-O-β-D-galactopyranoside

    		Others Others
    1,2-Di-O-linolenoylglycerol 3-O-β-D-galactopyranoside is a monogalactosyl diacylglycerol that can be found in the axenic cyanobacterium Phormidium tenue. 1,2-Di-O-linolenoylglycerol 3-O-β-D-galactopyranoside can induce lysis of Phormidium tenue .
    1,2-Di-O-linolenoylglycerol 3-O-β-D-galactopyranoside
  • HY-N19703
    (+)-Hydrangenol monomethyl ether

    4′-O-Methylhydrangenol

    		 Drug Isomer Others
    (+)-Hydrangenol monomethyl ether is a hydrangenol-monomethyl ether (+)-enantiomer found in axenic cultures of the liverwort Plagiochila adianthoides .
    (+)-Hydrangenol monomethyl ether
  • HY-180833
    Antileishmanial agent-39

    		Parasite Infection
    Antileishmanial agent-39 (Compound 4h) is an antileishmanial agent. Antileishmanial agent-39 shows antileishmanial activity against the axenic amastigote form of Leishmania infantum with an IC50 of 0.42 μM .
    Antileishmanial agent-39
  • HY-185556
    14-Hydroxydehydroabietane

    		Parasite Infection
    14-Hydroxydehydroabietane is a ribosomal enzyme inhibitor. 14-Hydroxydehydroabietane exhibits in vitro antileishmanial activity against promastigotes, amastigotes and intracellular amastigotes of *Leishmania infantum* and *Leishmania braziliensis*. 14-Hydroxydehydroabietane induces ultrastructural changes in *Leishmania braziliensis* promastigotes. 14-Hydroxydehydroabietane reduces the infection rate of macrophages by *Leishmania infantum* and *Leishmania braziliensis*. 14-Hydroxydehydroabietane can be used for the research of leishmaniasis .
    14-Hydroxydehydroabietane

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