67119-95-3
Chemical Structure
14-Hydroxydehydroabietane
- CAS No.: 67119-95-3
- Formula:C20H30O
- Molecular Weight:286.45
InChIKey: HOJWCCXHGGCJQV-FXAWDEMLSA-N
SMILES: [H][C@]1(CCC2=C3O)C(C)(C)CCC[C@]1(C)C2=CC=C3C(C)C
Biological Activity: 14-Hydroxydehydroabietane is a ribosomal enzyme inhibitor. 14-Hydroxydehydroabietane exhibits in vitro antileishmanial activity against promastigotes, amastigotes and intracellular amastigotes of Leishmania infantum and Leishmania braziliensis. 14-Hydroxydehydroabietane induces ultrastructural changes in Leishmania braziliensis promastigotes. 14-Hydroxydehydroabietane reduces the infection rate of macrophages by Leishmania infantum and Leishmania braziliensis. 14-Hydroxydehydroabietane can be used for the research of leishmaniasis[1].
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14-Hydroxydehydroabietane | 14-Hydroxydehydroabietane is a ribosomal enzyme inhibitor. 14-Hydroxydehydroabietane exhibits in vitro antileishmanial activity against promastigotes, amastigotes and intracellular amastigotes of Leishmania infantum and Leishmania braziliensis. 14-Hydroxydehydroabietane induces ultrastructural changes in Leishmania braziliensis promastigotes. 14-Hydroxydehydroabietane reduces the infection rate of macrophages by Leishmania infantum and Leishmania braziliensis. 14-Hydroxydehydroabietane can be used for the research of leishmaniasis. | |||||||||||||||||||||
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