Trypanothione synthetase-IN-3
Trypanothione synthetase-IN-3 is a noncompetitive mixed hyperbolic Trypanothione synthetase (TryS) inhibitor (Ki: 0.8 μM). Trypanothione synthetase-IN-3 can be used in the study of parasites, such as L. infantum.
For research use only. We do not sell to patients.
- CAS No.: 1314875-96-1
- Formula: C68H54O43
- Molecular Weight:1559.13
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Trypanothione synthetase (TryS)[1]
Trypanothione synthetase-IN-3 (30 min) displays noncompetitive inhibitory behavior against Li TryS with IC50 values of 2 μM -5.6 μM (determined by various substrates)[1].
Trypanothione synthetase-IN-3 (24 h) inhibits proliferation of L. infantum axenic amastigotes with an EC50 value of 43.7 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1314875-96-1
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Molecular Weight 1559.13
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Formula C68H54O43
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SMILES
O=C(C1=CC(O)=C(C(O)=C1)O)O[C@@H]2[C@H]([C@H](O[C@@H]([C@H]2OC(C3=CC(O)=C(C(O)=C3)O)=O)COC(C4=CC(O)=C(C(O)=C4)O)=O)O[C@@H]5[C@@H]([C@H]([C@@H]([C@H](O5)COC(C6=CC(O)=C(C(O)=C6)O)=O)OC(C7=CC(O)=C(C(O)=C7)O)=O)OC(C8=CC(O)=C(C(O)=C8)O)=O)OC(C9=CC(O)=C(C(O)=C9)O)=O)OC(C%10=CC(O)=C(C(O)=C%10)O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Trypanothione synthetase-IN-3 Related Classifications
HY-151151 Related Classifications
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