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Cat. No.: HY-180833

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Antileishmanial agent-39

Antileishmanial agent-39 (Compound 4h) is an antileishmanial agent. Antileishmanial agent-39 shows antileishmanial activity against the axenic amastigote form of Leishmania infantum with an IC₅₀ of 0.42 μM.

For research use only. We do not sell to patients.

Formula: C₂₂H₁₇BrCl₂N₄O₄S
Molecular Weight:584.27

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Antileishmanial agent-39 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

Leishmania

All Parasite Isoforms :

Chemical Information

Molecular Weight 584.27
Formula C₂₂H₁₇BrCl₂N₄O₄S
SMILES

ClC1=CC=CC(C(NS(C2=CC=C(C=C2)C)(=O)=O)CC3=C([N+]([O-])=O)N4C=C(Cl)C=C(Br)C4=N3)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jacquet I, et al. Discovery of antileishmanial hits in the 3-nitroimidazo[1,2-a]pyridine series via newly optimized tetrakis(dimethylamino)ethylene (TDAE) methodology at position 2. Eur J Med Chem. 2025 Dec 19;304:118506. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Antileishmanial agent-39

All Parasite Isoforms