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Results for "

baccatin III

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

4

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6985
    Baccatin III
    2 Publications Verification

    		 Others Cancer
    Baccatin III is an orally available, selective inhibitor of the TGF-β1 signaling pathway and myeloid-derived suppressor cell (MDSC) activation. Baccatin III targets the AKT/STAT6 and Smad2/3 pathways, blocking TGF-β1-induced fibroblast differentiation and MDSC-mediated immunosuppression. Baccatin III exerts anti-inflammatory and anti-fibrotic effects by inhibiting macrophage activation and extracellular matrix deposition, and shows potential in the treatment of pulmonary fibrosis and cancer in terms of regulating the tumor immune microenvironment .
    Baccatin III
  • HY-N6985R
    Baccatin III (Standard)

    		Reference Standards Others Cancer
    Baccatin III (Standard) is the analytical standard of Baccatin III. This product is intended for research and analytical applications. Baccatin III is a natural product isolated from Pacific yew tree and related species. Baccatin III reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs .
    Baccatin III (Standard)
  • HY-W777110
    7-(Triethylsilyl)baccatin III

    7-O-(Triethylsilyl)baccatin III

    		 Drug Intermediate Cancer
    7-(Triethylsilyl)baccatin III (7-O-(Triethylsilyl)baccatin III) is intermediate for preparation of the antitumor agent Paclitaxel (HY-B0015) .
    7-(Triethylsilyl)baccatin III
  • HY-N8070
    13-O-Cinnamoylbaccatin III

    baccatin III 13-cinnamate

    		 Drug Derivative Others
    13-O-Cinnamoylbaccatin III (Baccatin III 13-cinnamate) is a taxane that can be found in the twigs of Taxus mairei .
    13-O-Cinnamoylbaccatin III
  • HY-W778546
    7-epi-10-Deacetyl baccatin III

    		Others Cancer
    7-epi-10-Deacetyl baccatin III can be isolated from the degradation impurities in Docetaxel (HY-B0011) .
    7-epi-10-Deacetyl baccatin III
  • HY-W778547
    7-epi-10-Oxo-10-deacetyl baccatin III

    10-Dehydrobaccatin V

    		 Drug Intermediate Cancer
    7-epi-10-Oxo-10-deacetyl baccatin III (10-Dehydrobaccatin V) can be isolated from the degradation impurities in Docetaxel (HY-B0011) .
    7-epi-10-Oxo-10-deacetyl baccatin III
  • HY-W778558
    2-Debenzoyl-2-tigloyl 10-Deacetyl Baccatin III

    		Drug Derivative Others
    2-Debenzoyl-2-tigloyl 10-Deacetyl Baccatin III is a Baccatin III (HY-N6985) derivative lacking a benzoyl residue. 2-Debenzoyl-2-tigloyl 10-Deacetyl Baccatin III can be isolated from the needles of the European yew (T. barcata L.) .
    2-Debenzoyl-2-tigloyl 10-Deacetyl Baccatin III
  • HY-125374A
    Larotaxel dihydrate

    XRP9881 dihydrate

    		 Microtubule/Tubulin Cancer
    Larotaxel (dihydrate) (XRP9881 (dihydrate)), a new taxane compound prepared by partial synthesis from 10-deacetyl baccatin III, is active against tumors .
    Larotaxel dihydrate
  • HY-185269
    2'-Deoxy-PTX

    		Microtubule/Tubulin Drug Derivative Cancer
    2'-Deoxy-PTX is a Paclitaxel (HY-B0015) derivative and microtubule assembly inducer. 2'-Deoxy-PTX binds to GMPcPP-stabilized microtubules, with a Kaapp of 0.50 × 10 6 M -1. 2′-Deoxy-PTX induces Tubulin to assemble into normal microtubules. 2'-Deoxy-PTX can be used for the research of prostate cancer .
    2'-Deoxy-PTX

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