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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
cPLA2α
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "cPLA2α" in MCE Product Catalog:
8
8 Publications Verification
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CAY10650 is a highly potent cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 value of 12 nM. CAY10650 suppresses lipid droplets formation and PGE2 secretion [2].
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4 Cited Publications
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Pyrrophenone is a potent and specific cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 value of 4.2 nM .
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1 Cited Publications
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ASB14780 is a 4-phenoxy derivative, the cytosolic Phospholipase A2α (cPLA2α) inhibitor, with an IC50 value of 20 nM .
Cat. No.: HY-106253
CAS No.: 381683-94-9
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Efipladib is a potent, selective and orally active cPLA2α inhibitor with an IC50 of 0.04 μM and a Kd of 0.067 μM .
Cat. No.: HY-W019838S
CAS No.: 1246304-35-7
Synonyms: Sphinganine (d18:0)-d7
Cat. No.: HY-U00037
CAS No.: 381683-92-7
Synonyms: PLA 725
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Ecopladib is a sub-micromolar inhibitor of cytosolic phospholipase A2α (cPLA2α), with IC50s of 0.15 μM and 0.11 μM in the GLU micelle and rat whole blood assays, respectively.
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CAY10502 is a potent, calcium-dependent cytosolic phospholipase A2 α (cPLA2α) inhibitor with an IC50 of 4.3 nM for isolated enzyme. CAY10502 can be used in the research of retinopathy and inflammatory diseases [2] .
Cat. No.: HY-19920
CAS No.: 300553-18-8
Synonyms: AKH-217
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AVX001 is an inhibitor of phospholipase A2 (cPLA2α) that can be used in the research of psoriasis .
Cat. No.: HY-138871
CAS No.: 1233706-89-2
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cPLA2α-IN-derivative 1 is an inactive alcohol derivative of a highly potent Cytosolic phospholipase A2α (cPLA2α) inhibitor .
Cat. No.: HY-162368
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cPLA2α-IN-2 (Compound 122) is an inhibitor of cytosolic phospholipase A2α (cPLA2α) .
Cat. No.: HY-149654
CAS No.: 1696401-38-3
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FAAH/cPLA2α-IN-1 is a dual inhibitor of FAAH and cPLA2α with IC50s of 32 and 47 nM, respectively .
Cat. No.: HY-119094
CAS No.: 540523-42-0
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WAY-196025 is a selective and orally active indole cytosolic phospholipase A2 alpha (cPLA2α) inhibitor with an IC50 of 0.01μM and a Kd of 0.013 μM. WAY-196025 can inhibit the production of prostaglandins (such as PGE2) and leukotrienes (such as LTB4), and reduce the release of inflammatory mediators. WAY-196025 can be used for the researches of inflammation and immunology, such as asthma .
Cat. No.: HY-124852
CAS No.: 916136-25-9
Synonyms: PF 5212372
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ZPL-5212372 (PF 5212372) is a cPLA2α inhibitor (IC50 = 7 nM). ZPL-5212372 inhibits the release of prostaglandin D2 (PGD2), cysteyl leukotrienes, leukotriene B4, thromboxane A2, and PGD2 from human lung cells. ZPL-5212372 inhibits delayed bronchoconstriction and airway hyperresponsiveness in a sheep allergic inflammation model. ZPL-5212372 may be used in asthma research .
Cat. No.: HY-W019838R
CAS No.: 764-22-7
Synonyms: Sphinganine (d18:0) (Standard)
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Cat. No.: HY-111376R
CAS No.: 341973-06-6
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Pyrrophenone (Standard) is the analytical standard of Pyrrophenone (HY-111376). This product is intended for research and analytical applications. Pyrrophenone is a potent and specific cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 value of 4.2 nM .
Cat. No.: HY-10801R
CAS No.: 1233706-88-1
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CAY10650 (Standard) is the analytical standard of CAY10650 (HY-10801). This product is intended for research and analytical applications. CAY10650 is a highly potent cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 value of 12 nM. CAY10650 suppresses lipid droplets formation and PGE2 secretion [2].
Cat. No.: HY-P87025
Synonyms: Calcium dependent phospholipid binding protein antibody; cPLA 2 antibody; cPLA2 alpha antibody; cPLA2 antibody; Cytosolic phospholipase A2 antibody; Cytosolic phospholipase A2 group IVA antibody; Lysophospholipase antibody; MGC126350 antibody; PA24A_HUMAN antibody; Phosphatidylcholine 2 acylhydrolase antibody; Calcium dependent phospholipid binding protein antibody; cPLA 2 antibody; cPLA2 alpha antibody; cPLA2 antibody; Cytosolic phospholipase A2 antibody; Cytosolic phospholipase A2 group IVA antibody; Lysophospholipase antibody; MGC126350 antibody; PA24A_HUMAN antibody; Phosphatidylcholine 2 acylhydrolase antibody; Phosphatidylcholine 2-acylhydrolase antibody; Phospholipase A2 group 4 A antibody; Phospholipase A2 group IVA (cytosolic calcium dependent) antibody; Phospholipase A2 group IVA antibody; PhospholipaseA2 antibody; PLA2G4 antibody; pla2g4a antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
