300553-18-8
300553-18-8
Chemical Structure
AVX001
Synonym(s): AKH-217
- CAS No.: 300553-18-8
- Formula:C21H29F3OS
- Molecular Weight:386.51
IUPAC Name: 1,1,1-trifluoro-3-((2E,6Z,9Z,12Z,15Z)-octadeca-2,6,9,12,15-pentaen-1-ylthio)propan-2-one
InChIKey: RBPYIYOPSGHFQG-IIFHDYRKSA-N
SMILES: O=C(CSC/C=C/CC/C=C\C/C=C\C/C=C\C/C=C\CC)C(F)(F)F
Biological Activity: AVX001 is an inhibitor of phospholipase A2 (cPLA2α) that can be used in the research of psoriasis[1].
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AVX001 | AVX001 is an inhibitor of phospholipase A2 (cPLA2α) that can be used in the research of psoriasis. | |||||||||||||||||||||
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References
- [1]. S H Omland, et al. A randomized, double-blind, placebo-controlled, dose-escalation first-in-man study (phase 0) to assess the safety and efficacy of topical cytosolic phospholipase A2 inhibitor, AVX001, in patients with mild to moderate plaque psoriasis. J Eur Acad Dermatol Venereol. 2017 Jul;31(7):1161-1167. [Content Brief]
Keywords
