1069046-00-9
1069046-00-9
Chemical Structure
ASB14780
- CAS No.: 1069046-00-9
- Formula:C35H38N2O6
- Molecular Weight:582.69
IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol 3-(3-phenethyl-1-(4-phenoxyphenyl)-1H-indol-5-yl)propanoate
InChIKey: MBPXGBINIINSEU-UHFFFAOYSA-N
SMILES: O=C(CCC1=CC(C(CCC2=CC=CC=C2)=CN3C4=CC=C(C=C4)OC5=CC=CC=C5)=C3C=C1)O.OCC(CO)(CO)N
Biological Activity: ASB14780 is a 4-phenoxy derivative, the cytosolic Phospholipase A2α (cPLA2α) inhibitor, with an IC50 value of 20 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ASB14780 | 99.01% | ASB14780 is a 4-phenoxy derivative, the cytosolic Phospholipase A2α (cPLA2α) inhibitor, with an IC50 value of 20 nM. | ||||||||||||||||||||
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TRPM8 antagonist 2 | 98.09% | TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist, with an IC50 of 0.2 nM, used in the research of neuropathic pain syndromes. | ||||||||||||||||||||
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CYT-1010 | 99.28% | CYT-1010 is a mu-opioid receptor agonist extracted from patent WO2013173730A2, with EC50s of 13.1 nM and 0.0053 nM on beta-arrestin recruitment and inhibition of cAMP production, respectively. | ||||||||||||||||||||
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PSB-1737 | PSB-1737 is a human-selective GPR17 agonist with an EC50 for human GPR17 of 270 nM, and its activity on murine GPR17 is relatively weak (EC50 > 10 μM). PSB-1737 shows no significant inhibition at the glycine binding site of NMDA receptors, and has no significant agonistic or antagonistic activity on P2Y receptor subtypes. PSB-1737 can be used in demyelinating diseases (such as multiple sclerosis) or inflammatory-related anemia. | |||||||||||||||||||||
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GW9508 | 99.23% | GW9508 is a potent and selective G protein-coupled receptors FFA1 (GPR40) and GPR120 agonist with pEC50s of 7.32 and 5.46, respectively. GW9508 shows ~100-fold selectivity for GPR40 over GPR120. GW9508 is inactive against other GPCRs, kinases, proteases, integrins and PPARs. GW9508 is a glucose-sensitive insulin secretagogue and an ATP-sensitive potassium (KATP) channels opener. Anti-inflammatory and anti-atherosclerotic activities. | ||||||||||||||||||||
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DA-0218 | DA-0218 is a Nav1.7 inhibitor. DA-0218 exerts state-dependent inhibitory effects. DA-0218 alleviates formalin-induced inflammatory pain behavior and Paclitaxel-induced mechanical hyperalgesia in mice. DA-0218 inhibits Histamine-induced acute pruritus and lymphoma-induced chronic pruritus in mice. DA-0218 can be used in research related to inflammatory pain, neuropathic pain, acute pruritus and chronic pruritus. | |||||||||||||||||||||
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Endomorphin 1 | 99.67% | Endomorphin 1, a high affinity, highly selective agonist of the μ-opioid receptor (Ki: 1.11 nM), displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM. Endomorphin 1 has antinociceptive properties. | ||||||||||||||||||||
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Endomorphin 1 acetate | 99.92% | Endomorphin 1 acetate, a high affinity, highly selective agonist of the μ-opioid receptor (Ki: 1.11 nM), displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM. Endomorphin 1 acetate has antinociceptive properties. | ||||||||||||||||||||
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Tripeptide-41 | 99.30% | Tripeptide-41 (CG-Lipoxyn) is a signal peptide. Tripeptide-41 activates the NF-kB signaling pathway, inhibits the expression of C/EBP and increases cAMP. Tripeptide-41 is an important intracellular signaling factor that causes lipolysis by promoting the hydrolysis of lipids into triglycerides. Tripeptide-41 can be used in cosmetics that targets fat accumulation. | ||||||||||||||||||||
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9-(4'-Carboxy-[1,1'-biphenyl]-4-yl)-9H-carbazole-3,6-dicarboxylic acid | 9-(4'-Carboxy-[1,1'-biphenyl]-4-yl)-9H-carbazole-3,6-dicarboxylic acid is a metal-organic framework (MOF). | |||||||||||||||||||||
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4,4',4''-(9H-Carbazole-3,6,9-triyl)tribenzoic acid | 4,4',4''-(9H-Carbazole-3,6,9-triyl)tribenzoic acid is a metal-organic framework (MOF). | |||||||||||||||||||||
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