888320-29-4
888320-29-4
Chemical Structure
CAY10502
- CAS No.: 888320-29-4
- Formula:C30H37NO7
- Molecular Weight:523.62
IUPAC Name: 1-(3-(4-(decyloxy)phenoxy)-2-oxopropyl)-3-(methoxycarbonyl)-1H-indole-5-carboxylic acid
InChIKey: NXDZVUAKVFVDSL-UHFFFAOYSA-N
SMILES: O=C(C1=CN(CC(COC2=CC=C(OCCCCCCCCCC)C=C2)=O)C3=C1C=C(C(O)=O)C=C3)OC
Biological Activity: CAY10502 is a potent, calcium-dependent cytosolic phospholipase A2 α (cPLA2α) inhibitor with an IC50 of 4.3 nM for isolated enzyme. CAY10502 can be used in the research of retinopathy and inflammatory diseases[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CAY10502 | 98.72% | CAY10502 is a potent, calcium-dependent cytosolic phospholipase A2 α (cPLA2α) inhibitor with an IC50 of 4.3 nM for isolated enzyme. CAY10502 can be used in the research of retinopathy and inflammatory diseases. | ||||||||||||||||||||
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References
- [1]. Pohjala L L, et al. Interference by bovine serum albumin in PED6 based phospholipase A2 screening assays[J]. Die Pharmazie, 2012. [Content Brief]
- [2]. Barnett JM, et al. Role of cytosolic phospholipase A(2) in retinal neovascularization. Invest Ophthalmol Vis Sci. 2010;51(2):1136-1142. [Content Brief]
- [3]. Cui Y, et al. Exposure to extremely low-frequency electromagnetic fields inhibits T-type calcium channels via AA/LTE4 signaling pathway. Cell Calcium. 2014 Jan;55(1):48-58. [Content Brief]
Keywords
