381683-94-9
381683-94-9
Chemical Structure
Efipladib
- CAS No.: 381683-94-9
- Formula:C40H35Cl3N2O4S
- Molecular Weight:746.14
IUPAC Name: 4-(3-(1-benzhydryl-5-chloro-2-(2-(((3,4-dichlorophenyl)methyl)sulfonamido)ethyl)-1H-indol-3-yl)propyl)benzoic acid
InChIKey: HIZOPJQOPKRKFM-UHFFFAOYSA-N
SMILES: ClC1=C(Cl)C=CC(CS(NCCC2=C(CCCC3=CC=C(C(O)=O)C=C3)C4=CC(Cl)=CC=C4N2C(C5=CC=CC=C5)C6=CC=CC=C6)(=O)=O)=C1
Biological Activity: Efipladib is a potent, selective and orally active cPLA2α inhibitor with an IC50 of 0.04 μM and a Kd of 0.067 μM[1].
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Efipladib | Efipladib is a potent, selective and orally active cPLA2α inhibitor with an IC50 of 0.04 μM and a Kd of 0.067 μM. | |||||||||||||||||||||
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References
Keywords
