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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
cannabinoid ligand
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "cannabinoid ligand" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-W011051
CAS No.: 53847-30-6
Category:
1
1 Cited Publications
Synonyms: N-Docosahexaenoyl ethanolamine (DHEA); Docosahexaenoyl ethanolamide
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Synaptamide (Dehydroepiandrosteron; DHEA) is an endogenous metabolite and structural analogue of Anandamide. Synaptamide binds to both the cannabinoid-1 and 2 (CB1 and CB2) cannabinoid receptors and has anti-inflammatory properties. Synaptamide is the first small-molecule endogenous ligand of an adhesion G protein-coupled receptor (aGPCR) .
Cat. No.: HY-W011051S
CAS No.: 924894-97-3
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CB1/2 agonist 3 (compound 52), a potent non-selective cannabinoid ligand, is a CB1/CB2 (cannabinoid receptor) competitive agonist. CB1/2 agonist 3 acts on hCB1 and hCB2 with Ki values of 5.9 nM and 3.5 nM, respectively .
Cat. No.: HY-W011051S1
CAS No.: 2522598-88-3
Cat. No.: HY-134173
CAS No.: 183323-26-4
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Arachidonoyl ethanolamide phosphate, an endocannabinoid, is an endogenous ligand for cannabinoid receptors in the central nervous system (CB1 subtype) and peripheral immune cells (CB2 subtype) .
Cat. No.: HY-W013788
CAS No.: 23470-00-0
Synonyms: 2-Palm-Gl
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CB-25 is a ligand of CB1 cannabinoid receptors, acting as a partial agonist. CB-25 enhances Forskolin (HY-15371)-induced cAMP formation in cancer cells but not hCB1-CHO cells .
Cat. No.: HY-149933
CAS No.: 871978-21-1
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AM841 is a high-affinity electrophilic ligand. AM841 interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor. AM841 reduces Forskolin (HY-15371)-stimulated cAMP accumulation. AM841 also slows gastrointestinal motility .
Cat. No.: HY-175730
CAS No.: 2816933-22-7
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CB2R ligand-1 (Compound L14) is a selective Cannabinoid type 2 receptor (CB2R) ligand with a with Ki of 0.16 nM for CB2R over CB1R. CB2R ligand-1 as be used as a tracer for positron emission tomography (PET) imaging of neurodegenerative diseases, inflammation and cancer .
Cat. No.: HY-152576
CAS No.: 1817633-49-0
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CB2R agonist 1 is a selective ligand of cannabinoid receptor subtype 2 (CB2R) with an EC50 value of 0.56 µM. CB2R agonist 1 has high affinity and excellent selectivity for human CB2R and CB1R respectively. CB2R agonist 1 regulates the production of pro-inflammatory cytokines and anti-inflammatory cytokines and play an immunomodulatory role .
Cat. No.: HY-105238
CAS No.: 947696-17-5
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JHU-75528 is a novel ligand of the cannabinoid receptor (CB1). JHU-75528 can be used in the research of imaging CB1 receptor .
Cat. No.: HY-W011051S2
CAS No.: 2260670-54-8
Cat. No.: HY-168369
CAS No.: 501927-29-3
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Anti-inflammatory agent 94 (compound 4b) is a potent cannabinoid ligand with Kis of 29 nM and 8 nM against CB2 and CB1. Anti-inflammatory agent 94 can be utilized in inflammation rersearch .
Cat. No.: HY-150028
CAS No.: 2772379-97-0
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CB1/2 agonist 2 (compound 23) is a potent non-selective cannabinoid ligand, with Ki values of 3.5 and 1.2 nM, respectively. CB1/2 agonist 2 can behave as a full CB1 agonist and CB2 competitive inverse agonist. CB1/2 agonist 2 shows antinociceptive activity .
Cat. No.: HY-152270
CAS No.: 19825-63-9
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Pirnabine is a cannabinoid receptor ligand. Pirnabine can be used for the research of glaucoma .
Cat. No.: HY-121545
CAS No.: 869376-90-9
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CB-52 is the ligand and neutral antagonist of CB2 cannabinoid receptor .
Cat. No.: HY-120953
CAS No.: 1446648-15-2
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GAT228, the enantiomer of GAT211, is an allosteric cannabinoid receptor 1 (CB1) ligand .
Cat. No.: HY-115428
CAS No.: 220556-74-1
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(R)-(+)-Linoleyl-1'-Hydroxy-2'-Propylamide (Compound 19) is the analogue of endogenous cannabinoid receptor ligand Anandamide (HY-10863). (R)-(+)-Linoleyl-1'-Hydroxy-2'-Propylamide shows weak binding affinity for CB1 and CB2 with Kis of both 21 μM .
Cat. No.: HY-135881
CAS No.: 616884-66-3
Category:
Alkaloids Monophenols Neurological Disease Other Alkaloids Phenols Endogenous metabolite Disease Research Fields
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
