1. GPCR/G Protein Neuronal Signaling
  2. Cannabinoid Receptor
  3. CB-25

CB-25 is a ligand of CB1 cannabinoid receptors, acting as a partial agonist. CB-25 enhances Forskolin (HY-15371)-induced cAMP formation in cancer cells but not hCB1-CHO cells.

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CB-25 Chemical Structure

CB-25 Chemical Structure

CAS No. : 869376-63-6

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1 mg USD 50 In-stock
5 mg USD 110 In-stock
10 mg USD 190 In-stock
25 mg USD 400 In-stock
50 mg USD 640 In-stock
100 mg USD 1020 In-stock
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Description

CB-25 is a ligand of CB1 cannabinoid receptors, acting as a partial agonist. CB-25 enhances Forskolin (HY-15371)-induced cAMP formation in cancer cells but not hCB1-CHO cells[1].

Molecular Weight

403.60

Formula

C25H41NO3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC1CC1)CCCCCCCCCCOC2=CC(CCCCC)=CC(O)=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (247.77 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4777 mL 12.3885 mL 24.7770 mL
5 mM 0.4955 mL 2.4777 mL 4.9554 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4777 mL 12.3885 mL 24.7770 mL 61.9425 mL
5 mM 0.4955 mL 2.4777 mL 4.9554 mL 12.3885 mL
10 mM 0.2478 mL 1.2389 mL 2.4777 mL 6.1943 mL
15 mM 0.1652 mL 0.8259 mL 1.6518 mL 4.1295 mL
20 mM 0.1239 mL 0.6194 mL 1.2389 mL 3.0971 mL
25 mM 0.0991 mL 0.4955 mL 0.9911 mL 2.4777 mL
30 mM 0.0826 mL 0.4130 mL 0.8259 mL 2.0648 mL
40 mM 0.0619 mL 0.3097 mL 0.6194 mL 1.5486 mL
50 mM 0.0496 mL 0.2478 mL 0.4955 mL 1.2389 mL
60 mM 0.0413 mL 0.2065 mL 0.4130 mL 1.0324 mL
80 mM 0.0310 mL 0.1549 mL 0.3097 mL 0.7743 mL
100 mM 0.0248 mL 0.1239 mL 0.2478 mL 0.6194 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CB-25
Cat. No.:
HY-121541
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