CB-25
Based on 1 Customer Validation
CB-25 is a ligand of CB1 cannabinoid receptors, acting as a partial agonist. CB-25 enhances Forskolin (HY-15371)-induced cAMP formation in cancer cells but not hCB1-CHO cells.
For research use only. We do not sell to patients.
- Purity: 98.84%
- CAS No.: 869376-63-6
- Formula: C25H41NO3
- Molecular Weight:403.60
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RBL-2H3 | IC50 |
17 μM
Compound: 25
|
Inhibition of anandamide membrane transporter in RBL-2H3 cells assessed as [14C]anandamide uptake
Inhibition of anandamide membrane transporter in RBL-2H3 cells assessed as [14C]anandamide uptake
|
[PMID: 16279794] |
Chemical Information
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CAS No. 869376-63-6
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Appearance Solid
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Molecular Weight 403.60
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Formula C25H41NO3
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Color White to off-white
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SMILES
O=C(NC1CC1)CCCCCCCCCCOC2=CC(CCCCC)=CC(O)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (247.77 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (263 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4777 mL | 12.3885 mL | 24.7770 mL | 61.9425 mL |
| 5 mM | 0.4955 mL | 2.4777 mL | 4.9554 mL | 12.3885 mL | |
| 10 mM | 0.2478 mL | 1.2389 mL | 2.4777 mL | 6.1943 mL | |
| 15 mM | 0.1652 mL | 0.8259 mL | 1.6518 mL | 4.1295 mL | |
| 20 mM | 0.1239 mL | 0.6194 mL | 1.2389 mL | 3.0971 mL | |
| 25 mM | 0.0991 mL | 0.4955 mL | 0.9911 mL | 2.4777 mL | |
| 30 mM | 0.0826 mL | 0.4130 mL | 0.8259 mL | 2.0648 mL | |
| 40 mM | 0.0619 mL | 0.3097 mL | 0.6194 mL | 1.5486 mL | |
| 50 mM | 0.0496 mL | 0.2478 mL | 0.4955 mL | 1.2389 mL | |
| 60 mM | 0.0413 mL | 0.2065 mL | 0.4130 mL | 1.0324 mL | |
| 80 mM | 0.0310 mL | 0.1549 mL | 0.3097 mL | 0.7743 mL | |
| 100 mM | 0.0248 mL | 0.1239 mL | 0.2478 mL | 0.6194 mL |