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capsules

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31

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N7033

    Uridine 5'-diphosphoglucuronic acid trisodium salt

    Drug Intermediate Metabolic Disease
    UDP-​glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates across biological kingdoms, ranging from mammalian glycosaminoglycans and plant cell wall polysaccharides to bacterial capsule glycoglycerolipids.
    UDP-glucuronic acid trisodium
  • HY-Y0873M

    Polyethylene glycol 500

    Environmental Pollutants Biochemical Assay Reagents Others
    PEG500 (Polyethylene glycol 500) is a versatile polymer that's used as a solvent, dispersant, lubricant, and more in industries like pharmaceuticals and biotechnology, and it can also modify liposomes. PEG500 is commonly used as a solvent or carrier for drugs, helping with capsule endoscopy to improve image quality and cecum completion rates .
    PEG500
  • HY-B1888B

    Bromfenac monosodium salt sesquihydrate

    COX Infection Inflammation/Immunology
    Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. Bromfenac sodium hydrate can be used in ocular inflammation research .
    Bromfenac sodium hydrate
  • HY-100897

    Thrombin Cardiovascular Disease
    Sulodexide is a mixture of glycosaminoglycans available in soft capsule form for oral administration. It is composed of low molecular weight heparin (80%) and dermatan sulfate (20%). Sulodexide exhibits antithrombotic activity through interaction with antithrombin III (AT III) and heparin cofactor II (HC II), and inhibition of thrombin formation. Sulodexide exhibits profibrinolytic activity through release of tissue plasminogen activator (tPA). Sulodexide exhibits endothelial protective and anti-inflammatory effect, ameliorates chronic venous disease . Sulodexide is a glycosaminoglycan mixture available in soft gelatin capsule form for oral administration.
    Sulodexide
  • HY-B1888A

    COX Infection Inflammation/Immunology
    Bromfenac sodium is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. Bromfenac sodium can be used in ocular inflammation research .
    Bromfenac sodium
  • HY-78727

    IBT4A

    Drug Intermediate Btk Inflammation/Immunology Cancer
    Ibrutinib deacryloylpiperidine (IBT4A) is a derivative of an Ibrutinib (HY-10997) intermediate and an Ibrutinib impurity. Ibrutinib deacryloylpiperidine serves as a starting material and is used in the synthesis of a modified BTK inhibitor derivative via the Mitsunobu reaction .
    Ibrutinib deacryloylpiperidine
  • HY-A0104B

    Hypromellose (Type I,Viscosity:100mPa.s); (Hydroxypropyl)methyl cellulose (Type I,Viscosity:100mPa.s); Celacol HPM 5000 (Type I,Viscosity:100mPa.s)

    Environmental Pollutants Biochemical Assay Reagents Others
    HPMC (Type I, Viscosity: 100 mPa·s) is a nonionic polymer obtained via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, including the diffusion of drugs within the hydrated matrix and the polymer relaxation process .
    HPMC (Type I,Viscosity:100mPa.s)
  • HY-145533

    KDN

    Biochemical Assay Reagents Others
    3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) is a type of sialic acid. 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid can be hydrolyzed by sialidase from the loach (Misgurnus fossilis) .
    3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid
  • HY-N7033R

    Uridine 5'-diphosphoglucuronic acid trisodium salt (Standard)

    Reference Standards Drug Intermediate Metabolic Disease
    UDP-glucuronic acid (trisodium) (Standard) is the analytical standard of UDP-glucuronic acid (trisodium). This product is intended for research and analytical applications. UDP-?glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates across biological kingdoms, ranging from mammalian glycosaminoglycans and plant cell wall polysaccharides to bacterial capsule glycoglycerolipids.
    UDP-glucuronic acid trisodium (Standard)
  • HY-B1888

    COX Infection Inflammation/Immunology
    Bromfenac is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. Bromfenac can be used in ocular inflammation research .
    Bromfenac
  • HY-157049

    Biochemical Assay Reagents Others
    Caprylocaproyl Macrogolglycerides is a lipoidic excipient/vehicle in an oral capsule formulation. Caprylocaproyl Macrogolglycerides can enhance the absorption of small molecule compounds .
    Caprylocaproyl Macrogolglycerides
  • HY-129502

    P-23924C

    HIF/HIF Prolyl-Hydroxylase Others
    Fibrostatin C (P-23924C) is an orally active prolyl hydroxylase inhibitor that also inhibits collagen biosynthesis. Fibrostatin C also increases the number of cytoplasmic granules immunoreactive with antibodies to collagen I or III. Fibrostatin C inhibits the secretion of type I collagen in Tenon's capsule fibroblasts. Fibrostatin C is promising for research of the wound fibrotic response in the wound of glaucoma filtering surgery .
    Fibrostatin C
  • HY-N11102

    dTDP-L-Rhamnose

    Endogenous Metabolite Bacterial Infection
    Thymidine-5'-diphosphate-L-rhamnose (dTDP-L-Rhamnose) is a key activated nucleotide sugar in bacteria, with a KD value of 13 μM for Listeria monocytogenes RmlT. Thymidine-5'-diphosphate-L-rhamnose acts as a high-energy donor for L-Rhamnose (HY-N1420), and is specifically used for the synthesis of bacterial cell wall polysaccharides, capsules and virulence factors .
    Thymidine-5'-diphosphate-L-rhamnose
  • HY-P11100

    Bacterial Infection
    PepW is a potent antimicrobial peptide targeting the capsule of multidrug-resistant Klebsiella pneumoniae (MIC=2-8 μM). PepW achieves bactericidal activity via capsule polysaccharide aggregation and structural disruption. PepW is promising for research of infectious diseases caused by Gram-negative bacteria (e.g., pneumonia, sepsis) .
    PepW
  • HY-154313

    Clospirazine

    Ras Cancer
    Spiclomazine (Clospirazine) is a potent mutant KRAS(G12C) inhibitor that selectively inhibits mutant KRAS-driven pancreatic cancer. Spiclomazine can eliminate KRas-GTP levels in KRAS-driven pancreatic cancer and effectively inhibit RAS-mediated signaling. Spiclomazine significantly inhibits tumor progression in mouse renal capsule xenotransplantation models .
    Spiclomazine
  • HY-N11102A

    dTDP-L-Rhamnose disodium

    Endogenous Metabolite Bacterial Infection
    Thymidine-5'-diphosphate-L-rhamnose (dTDP-L-Rhamnose) disodium is a key activated nucleotide sugar in bacteria, with a KD value of 13 μM for Listeria monocytogenes RmlT. Thymidine-5'-diphosphate-L-rhamnose disodium acts as a high-energy donor for L-Rhamnose (HY-N1420), and is specifically used for the synthesis of bacterial cell wall polysaccharides, capsules and virulence factors .
    Thymidine-5'-diphosphate-L-rhamnose disodium
  • HY-W127851

    Cypridina luciferin analog

    Biochemical Assay Reagents Others Cancer
    CLA, or conjugated linoleic acid, is a polyunsaturated fatty acid that occurs naturally in a variety of animal products, such as meat and dairy. It has several potential benefits for human health, including the ability to reduce body fat mass, improve insulin sensitivity, and reduce inflammation. CLA has been extensively studied for its effects on weight loss and muscle growth, as well as its potential role in preventing chronic diseases such as heart disease and cancer. Additionally, it can be taken as a dietary supplement in capsule form.
    CLA
  • HY-B1888AR

    COX Reference Standards Infection Inflammation/Immunology
    Bromfenac (sodium) (Standard) is the analytical standard of Bromfenac (sodium). This product is intended for research and analytical applications. Bromfenac sodium is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. Bromfenac sodium can be used in ocular inflammation research .
    Bromfenac sodium (Standard)
  • HY-154703

    Biochemical Assay Reagents Others
    Aluminum magnesium silicate can be used as an excipient, such as adsorbent, stabilizer, suspending agent, disintegrant for tablet and capsule, binder for tablet, thickener. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
    Aluminum magnesium silicate
  • HY-153771

    Bacterial Infection
    Du011 is an E. coli polysaccharide capsule biogenesis inhibitor that targets MprA. Du011 can be used in research against E. coli infection .
    Du011
  • HY-113002

    Phosphomannose Isomerase (PMI) Infection Metabolic Disease
    α-D-Glucose 1,6-bisphosphate is an activator of PMM2 and phosphoglucomutase. α-D-Glucose 1,6-bisphosphate regulates glycogen metabolism, glycolysis, amino sugar synthesis, as well as the formation of bacterial cell walls and capsules. α-D-Glucose 1,6-bisphosphate can be used in studies related to pmm2-cdg (cdg-1a or Jaeken syndrome) .
    α-D-Glucose 1,6-bisphosphate
  • HY-169919

    Histone Demethylase Fungal Infection
    HDM-IN-1 (Compound A4) is an inhibitor for fungal histone demethylase (HDM), that inhibits the H3K27me3 in Cryptococcus neoformans and in Candida auris with IC50s of 134 and 12 nM. HDM-IN-1 exhibits inhibitory efficacy against C. neoformans and C. auris with MIC80 of 0.5-2 μg/mL, through inhibition of the biofilm and capsule formation. HDM-IN-1 exhibits antifungal activity in ICR mouse model .
    HDM-IN-1
  • HY-167680

    GSK823093

    Endogenous Metabolite Metabolic Disease
    Denagliptin (GSK823093) is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor with activity for the suppression of endocrine and metabolic diseases. Denagliptin can be used to study type 2 diabetes. Denagliptin is stable in the solid state but degrades in solution and in mixtures with various excipients. Denagliptin also exhibits degradation in capsules, mainly through cyclization reactions to form (3S,7S,8aS) aminoamines to provide further synthetic materials. The degradation pathway of Denagliptin was elucidated, providing data to support its formulation development and regulatory filings .
    Denagliptin
  • HY-173428

    Fungal Infection
    Antifungal agent 130 (Compound A7) is an orally active antifungal agent. Antifungal agent 130 has good antifungal activity against Candida albicans (MIC = 0.12 ng/mL) and Cryptococcus neoformans (MIC = 0.12 ng/mL) and has excellent antivirulence effect. Antifungal agent 130 exerts its antifungal effect by disrupting the iron homeostasis of fungal cells and inducing oxidative stress damage. Antifungal agent 130 can inhibit the formation of fungal virulence factors (such as biofilm, capsule, urease and melanin). Antifungal agent 130 has good antifungal effect and can be used in the study of drug-resistant fungal infections .
    Antifungal agent 130
  • HY-B1888BR

    Bromfenac monosodium salt sesquihydrate (Standard)

    COX Reference Standards Infection Inflammation/Immunology
    Bromfenac (sodium hydrate) (Standard) is the analytical standard of Bromfenac (sodium hydrate). This product is intended for research and analytical applications. Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. Bromfenac sodium hydrate can be used in ocular inflammation research .
    Bromfenac sodium hydrate (Standard)
  • HY-185260

    Liposome Cancer
    AA76-lipid (Compound aa76) is a compound with a C-terminal arginine and histidine. AA76-lipid can be used to prepare pancreas-targeted lipid nanoparticles AH-LNP. After assembling with proteins, the increased size of AH-LNP promotes Capsule-filter-mediated selective accumulation in the pancreas and receptor-mediated endocytosis, thereby enhancing pancreas-targeting ability. AA76-lipid enables highly pancreas-selective delivery of mRNA. AA76-lipid can be used in the research of pancreatic cancer .
    AA76-lipid
  • HY-182743

    AMPK MARK YAP Cancer
    OICR19451 is an orally active dual NUAK1/NUAK2 and MARK2/MARK3 kinase inhibitor, with IC50 values of 12 nM and 10 nM against NUAK1 and NUAK2, and 101 nM and 124 nM against MARK2 and MARK3, respectively. OICR19451 modulates the Hippo signaling pathway, increases the phosphorylation level of YAP, enhances the cytoplasmic localization of YAP/TAZ, and inhibits the expression of oncogenes. OICR19451 inhibits cancer cell growth, reduces metastasis, promotes tumor capsule formation, and improves mouse survival in an orthotopic breast cancer model. OICR19451 can be used for research related to triple-negative breast cancer .
    OICR19451
  • HY-W142283

    Drug Derivative Others
    2,3-Dimethylfuran is a furan derivative. 2,3-Dimethylfuran can be formed by the cyclization of (Z)-3-methylpent-2-en-4-yn-1-ol by various methods .
    2,3-Dimethylfuran
  • HY-N17727

    Interleukin Related TNF Receptor Neurological Disease Inflammation/Immunology
    Divaricatol is an orally ative chromone natural product and an active component in Saposhnikovia divaricata. Divaricatol reduces the release of pro-inflammatory cytokines and restores immune homeostasis by stably binding to 5KIR (a target of the TNF/IL-17 pathway). Divaricatol exerts analgesic effects in mouse models. Divaricatol can be used in the research of pain, diarrhea-predominant irritable bowel syndrome (IBS-D) and qi deficiency syndrome .
    Divaricatol
  • HY-N17737

    Fatty Acid Synthase (FASN) Cytochrome P450 Metabolic Disease Inflammation/Immunology
    Floramanoside F is a type of flavonol glycoside compound. Floramanoside F has a moderate free radical scavenging effect, with a SC₅₀ value of 25.1 μM. Floramanoside F has a relatively weak inhibitory activity on aldose reductase, with a IC₅₀ value greater than 100 μM. Floramanoside F has strong binding affinity with key target enzymes of type 1 diabetic nephropathy (T1DN) (Fasn, Cyp2e1, Cyp4a32), and can inhibit lipid accumulation and oxidative stress, thereby alleviating renal inflammation and fibrosis. Floramanoside F can be used to study type 1 diabetic nephropathy and diabetic complications .
    Floramanoside F
  • HY-P992076

    TGF-β Receptor TGF-beta/Smad Cholinesterase (ChE) Fungal Infection Cancer
    Anti-Candida auris β-1,3-glucans Antibody (2G8) is an antibody targeting Candida auris β-1,3-glucans, and also acts as an inhibitor of AChE and TGF-β receptor 2. Anti-Candida auris β-1,3-glucans Antibody (2G8) also targets fungal cell wall components, effectively inhibits fungal growth and interferes with capsule formation, thereby significantly reducing the fungal load in mouse tissues. Anti-Candida auris β-1,3-glucans Antibody (2G8) not only blocks TGF-β receptor binding to inhibit the Smad signaling pathway, reduces fibroblast activation and collagen deposition, but also induces epithelial differentiation of tumor cells and reduces pancreatic tumor metastasis. Anti-Candida auris β-1,3-glucans Antibody (2G8) specifically binds to the conserved N-linked glycoepitope on AChE to inhibit its activity without interfering with BChE, and can be used in studies of cryptococcosis and related tumor mechanisms .The isotype control is Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-Candida auris β-1, 3 glucans Antibody (2G8)

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