214753-67-0
Chemical Structure
Thymidine-5'-diphosphate-L-rhamnose disodium
Synonym(s): dTDP-L-Rhamnose disodium
- CAS No.: 214753-67-0
- Formula:C16H24N2Na2O15P2
- Molecular Weight:592.29
IUPAC Name: (2-ethyl-2-methyl-1,3-dioxolan-4-yl)methyl acrylate
InChIKey: QEUPXBDYSWMXJF-NAIDCLSWSA-L
SMILES: O[C@H]1C[C@H](N2C=C(C)C(NC2=O)=O)O[C@@H]1COP(OP(O[C@@H]3[C@@H]([C@@H]([C@H]([C@@H](O3)C)O)O)O)(O[Na])=O)(O[Na])=O
Biological Activity: Thymidine-5'-diphosphate-L-rhamnose (dTDP-L-Rhamnose) disodium is a key activated nucleotide sugar in bacteria, with a KD value of 13 μM for Listeria monocytogenes RmlT. Thymidine-5'-diphosphate-L-rhamnose disodium acts as a high-energy donor for L-Rhamnose (HY-N1420), and is specifically used for the synthesis of bacterial cell wall polysaccharides, capsules and virulence factors[1][2].
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Thymidine-5'-diphosphate-L-rhamnose disodium | Thymidine-5'-diphosphate-L-rhamnose (dTDP-L-Rhamnose) disodium is a key activated nucleotide sugar in bacteria, with a KD value of 13 μM for Listeria monocytogenes RmlT. Thymidine-5'-diphosphate-L-rhamnose disodium acts as a high-energy donor for L-Rhamnose (HY-N1420), and is specifically used for the synthesis of bacterial cell wall polysaccharides, capsules and virulence factors. | |||||||||||||||||||||
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References
- [1]. Monteiro R, et al. Molecular properties of the RmlT wall teichoic acid rhamnosyltransferase that modulates virulence in Listeria monocytogenes. Nat Commun. 2025;16(1):24. Published 2025 Jan 2. [Content Brief]
- [2]. Coelho JF. Biosynthesis, Isolation and Magnetization of gellan spheres for biorecognition of therapeutic His-tag proteins (Master's thesis, Universidade da Beira Interior (Portugal)).
