330786-24-8
330786-24-8
Chemical Structure
Ibrutinib deacryloylpiperidine
Synonym(s): IBT4A
- CAS No.: 330786-24-8
- Formula:C17H13N5O
- Molecular Weight:303.32
IUPAC Name: 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
InChIKey: YYVUOZULIDAKRN-UHFFFAOYSA-N
SMILES: NC1=C2C(NN=C2C3=CC=C(OC4=CC=CC=C4)C=C3)=NC=N1
Biological Activity: Ibrutinib deacryloylpiperidine (IBT4A) is a derivative of an Ibrutinib (HY-10997) intermediate and an Ibrutinib impurity. Ibrutinib deacryloylpiperidine serves as a starting material and is used in the synthesis of a modified BTK inhibitor derivative via the Mitsunobu reaction[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ibrutinib deacryloylpiperidine | 99.96% | Ibrutinib deacryloylpiperidine (IBT4A) is a derivative of an Ibrutinib (HY-10997) intermediate and an Ibrutinib impurity. Ibrutinib deacryloylpiperidine serves as a starting material and is used in the synthesis of a modified BTK inhibitor derivative via the Mitsunobu reaction. | ||||||||||||||||||||
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References
- [1]. Zeng S, et al. Synthesis and Structural Characterization of an Ibrutinib Intermediate Derivative: A Comprehensive Experiment for Undergraduate Students of Medicinal Chemistry[J]. Journal of Chemical Education, 2026.
- [2]. Prasad S S, et al. A quality by design approach for development of simple and robust reversed phase stability indicating HPLC method for estimation of ibrutinib and its impurities[J]. analytical methods, 2019, 12(3): 1434-1445.
