28 Results for "

dynorphin

" in MedChemExpress (MCE) Product Catalog:
Products (28)

28 Results for "dynorphin" in MCE Product Catalog:

8
8 Publications Verification
Cat. No.: HY-117040
CAS No.: 105618-26-6
Purity:  98.70%
Synonyms: Norbinaltorphimine; NorBNI
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

nor-Binaltorphimine (Norbinaltorphimine; NorBNI) is a selective, long-acting competitive antagonist of the κ-opioid receptor. nor-Binaltorphimine blocks κ-opioid receptor-mediated analgesic effects, and inhibits butorphanol-induced changes in κ-opioid receptor binding kinetics, desensitization and down-regulation. nor-Binaltorphimine suppresses specific opioid withdrawal symptoms, precipitates withdrawal behaviors in butorphanol-dependent rats, and serves as a molecular probe for studying κ-opioid receptor-agonist interactions. nor-Binaltorphimine is applicable to research related to neurological disorders such as pain .
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2
2 Cited Publications
Cat. No.: HY-P1333
CAS No.: 80448-90-4
Dynorphin A is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS). Dynorphin A is a highy potent kappa opioid receptor (KOR) agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR). Dynorphin A can induce neuronal death, and can be used in the research of neurological disease .
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1
1 Cited Publications
Cat. No.: HY-B0188A
CAS No.: 21535-47-7
Synonyms: Org GB 94
Mianserin hydrochloride (Org GB 94) is an orally active H1 receptor antagonist. Mianserin hydrochloride can activate κ-opioid receptor and octopamine receptor. Mianserin hydrochloride increases ERK1/2 and CREB phosphorylation, and antagonizes full κ-opioid agonist and Dynorphin A (HY-P1333)-induced MAPK phosphorylation. Mianserin hydrochloride modulates social and exploratory behaviour, raises electroconvulsive thresholds. Mianserin hydrochloride can be used for the research of neurological disease, such as depression and epilepsy .
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1
1 Cited Publications
Cat. No.: HY-B0188
CAS No.: 24219-97-4
Synonyms: Mianserine
Mianserin (Mianserine) is an orally active H1 receptor antagonist. Mianserin can activate κ-opioid receptor and octopamine receptor. Mianserin increases ERK1/2 and CREB phosphorylation, and antagonizes full κ-opioid agonist and Dynorphin A (HY-P1333)-induced MAPK phosphorylation. Mianserin modulates social and exploratory behaviour, raises electroconvulsive thresholds. Mianserin can be used for the research of neurological disease, such as depression and epilepsy .
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1
1 Cited Publications
Cat. No.: HY-P1337
CAS No.: 83335-41-5
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.
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1
1 Cited Publications
Cat. No.: HY-P1337A
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

Dynorphin B (1-13) TFA acts as an agonist on opioid κ-receptor.
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Cat. No.: HY-P2159
CAS No.: 75790-53-3
Dynorphin A (1-8) is a ligand with preference for the κ-opioid receptor, and its IC50 value against human placental κ-opioid receptor is 330 nM. Dynorphin A (1-8) mediates neuroprotective effects by inhibiting oxidative stress, suppressing apoptosis, and competitively displacing the binding of κ partial agonists. Dynorphin A (1-8) is the dominant opioid peptide in human placental villi and tissue extracts; it undergoes rapid hydrolysis and can enter the central nervous system via intranasal administration. Dynorphin A (1-8) can be used in studies related to ischemic stroke .
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Cat. No.: HY-P0088
CAS No.: 72957-38-1
Synonyms: dynorphin A Porcine Fragment 1-13
Target:  

Opioid Receptor

Research Areas:  

Others

Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations.
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Cat. No.: HY-P1594A
Target:  

Opioid Receptor iGluR

Research Areas:  

Neurological Disease

Dynorphin A (1-10) (TFA), an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor. Dynorphin A (1-10) (TFA) also blocks NMDA-activated current with an IC50 of 42.0 μM.
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Cat. No.: HY-P3646
CAS No.: 95673-38-4
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

[DAla2] Dynorphin A (1-9) (porcine) is a dynorphin, which can be used in studies of analgesic, addiction, and depression.
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Cat. No.: HY-P3632
CAS No.: 75921-88-9
Synonyms: DADAD
Target:  

Opioid Receptor

[DAla2, DArg6] Dynorphin A, (1-13) (porcine) (DADAD) is an opioid peptide (dynorphinl-13, DYN) derivative found in porcine pituitary extracts. DYN is highly potent at the peripheral opioid receptors GPI and MVD, but is readily and rapidly degraded in vivo. [DAla2, DArg6] Dynorphin A, (1-13) (porcine) has some resistance to enzymatic cleavage and prevents peptide cleavage by enzymes .
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Cat. No.: HY-B0188AR
CAS No.: 21535-47-7
Synonyms: Org GB 94 (Standard)
Mianserin hydrochloride (Org GB 94) (Standard) is the analytical standard of Mianserin hydrochloride. This product is intended for research and analytical applications. Mianserin hydrochloride is an orally active H1 receptor antagonist. Mianserin hydrochloride can activate κ-opioid receptor and octopamine receptor. Mianserin hydrochloride increases ERK1/2 and CREB phosphorylation, and antagonizes full κ-opioid agonist and Dynorphin A (HY-P1333)-induced MAPK phosphorylation. Mianserin hydrochloride modulates social and exploratory behaviour, raises electroconvulsive thresholds. Mianserin hydrochloride can be used for the research of neurological disease, such as depression and epilepsy .
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Cat. No.: HY-B0188S
CAS No.: 81957-76-8
Synonyms: Mianserine-d3
Mianserin-d3 is the deuterium labeled Mianserin (HY-B0188). Mianserin (Mianserine) is an orally active H1 receptor antagonist. Mianserin can activate κ-opioid receptor and octopamine receptor. Mianserin increases ERK1/2 and CREB phosphorylation, and antagonizes full κ-opioid agonist and Dynorphin A (HY-P1333)-induced MAPK phosphorylation. Mianserin modulates social and exploratory behaviour, raises electroconvulsive thresholds. Mianserin can be used for the research of neurological disease, such as depression and epilepsy .
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Cat. No.: HY-P1594
CAS No.: 79994-24-4
Target:  

Opioid Receptor iGluR

Research Areas:  

Neurological Disease

Dynorphin A (1-10) an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor. Dynorphin A (1-10) also blocks NMDA-activated current with an IC50 of 42.0 μM.
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Cat. No.: HY-P3628
CAS No.: 83608-80-4
Target:  

Peptides

Research Areas:  

Neurological Disease

Dynorphin (2-17) (porcine) is a peptide derived from Prodynorphin, can improve somatic signs of Morphine-dependent withdrawal .
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Cat. No.: HY-P1625
CAS No.: 103614-28-4
Synonyms: dynorphin A ethylamide (1-9)
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

Daeatal (Dynorphin A ethylamide (1-9)) is an ethylamine-modified dynorphin fragment that can be used in the study of analgesia, addiction, depression, etc. Dynorphin A is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS). Dynorphin A is a highy potent kappa opioid receptor (KOR) agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR). Dynorphin A can induce neuronal death, and can be used in the research of neurological disease .
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Cat. No.: HY-P3625
CAS No.: 161874-98-2
Dynorphin (2-17), amide (porcine) is a dynorphin derivative with some analgesic effects. Dynorphin is a class of opioid peptides produced by the precursor protein dynorphinogen and is involved in pain, addiction and mood regulation .
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Cat. No.: HY-B0188AS
CAS No.: 1219804-97-3
Synonyms: Org GB 94-d3
Mianserin-d3 hydrochloride is the deuterium labeled Mianserin. Mianserin (Mianserine) is an orally active H1 receptor antagonist. Mianserin can activate κ-opioid receptor and octopamine receptor. Mianserin increases ERK1/2 and CREB phosphorylation, and antagonizes full κ-opioid agonist and Dynorphin A (HY-P1333)-induced MAPK phosphorylation. Mianserin modulates social and exploratory behaviour, raises electroconvulsive thresholds. Mianserin can be used for the research of neurological disease, such as depression and epilepsy .
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Cat. No.: HY-P5826
CAS No.: 126050-26-8
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

Dynorphin B (1-9) is a neuropeptide and N-terminal cleavage product of dynorphin B. The formation of dynorphin B (1-9) is blocked by N-ethylmaleimide (NEM), a non-selective inhibitor of cysteine peptidases .
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Cat. No.: HY-P1333A
Dynorphin A TFA is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS). Dynorphin A TFA is a highy potent kappa opioid receptor (KOR) agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR). Dynorphin A TFA can induce neuronal death, and can be used in the research of neurological disease .
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