1. GPCR/G Protein
    Neuronal Signaling
  2. Opioid Receptor
  3. Porcine dynorphin A(1-13)

Porcine dynorphin A(1-13) (Synonyms: Dynorphin A Porcine Fragment 1-13)

Cat. No.: HY-P0088 Purity: 98.99%
Handling Instructions

Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Porcine dynorphin A(1-13) Chemical Structure

Porcine dynorphin A(1-13) Chemical Structure

CAS No. : 72957-38-1

Size Price Stock Quantity
1 mg USD 84 In-stock
Estimated Time of Arrival: December 31
5 mg USD 180 In-stock
Estimated Time of Arrival: December 31
10 mg USD 288 In-stock
Estimated Time of Arrival: December 31
25 mg USD 588 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations.

IC50 & Target

Κ opioid receptor[1].

In Vivo

Dynorphin A (1-13) exposure (33 μM) causes a significant loss in neuronal viability at 4 h with a visible destruction in neuronal morphology seen at 16 h. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment. Continuous exposure to dynorphin A (1-13) (100 μM) causes a significant loss of neurons over time[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1603.96

Formula

C₇₅H₁₂₆N₂₄O₁₅

CAS No.
Sequence

Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys

Sequence Shortening

YGGFLRRIRPKLK

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -80°C 2 years
-20°C 1 year
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 60 mg/mL (37.41 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6235 mL 3.1173 mL 6.2346 mL
5 mM 0.1247 mL 0.6235 mL 1.2469 mL
10 mM 0.0623 mL 0.3117 mL 0.6235 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Porcine dynorphin A(1-13)Dynorphin A Porcine Fragment 1-13Opioid ReceptorInhibitorinhibitorinhibit

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Product Name:
Porcine dynorphin A(1-13)
Cat. No.:
HY-P0088
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