Isosteric replacement of acidic with neutral residues in extracellular loop-2 of the kappa-opioid receptor does not affect dynorphin A(1-13) affinity and function

  • J Med Chem. 2000 Apr 6;43(7):1251-2. doi: 10.1021/jm990583r.
D M Ferguson  1 ,  S Kramer ,  T G Metzger ,  P Y Law ,  P S Portoghese
Affiliations
  • 1. Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota 55455, USA.
PMID: 10753461 DOI: 10.1021/jm990583r