1. GPCR/G Protein
    Neuronal Signaling
  2. Opioid Receptor

Naloxegol oxalate (Synonyms: NKTR-118 oxalate; AZ-13337019 oxalate)

Cat. No.: HY-A0118A Purity: 99.90%
Handling Instructions

Naloxegol oxalate (NKTR-118 oxalate; AZ-13337019 oxalate) is an opioid-receptor antagonist.

For research use only. We do not sell to patients.

Naloxegol oxalate Chemical Structure

Naloxegol oxalate Chemical Structure

CAS No. : 1354744-91-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 571 In-stock
Estimated Time of Arrival: December 31
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 500 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1500 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2100 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Description

Naloxegol oxalate (NKTR-118 oxalate; AZ-13337019 oxalate) is an opioid-receptor antagonist[1].

IC50 & Target

Opioid receptor[1]

Solvent & Solubility
In Vitro: 

DMSO : ≥ 40 mg/mL (53.92 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3480 mL 6.7402 mL 13.4804 mL
5 mM 0.2696 mL 1.3480 mL 2.6961 mL
10 mM 0.1348 mL 0.6740 mL 1.3480 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (2.80 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (2.80 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (2.80 mM); Clear solution

References
Molecular Weight

741.82

Formula

C₃₆H₅₅NO₁₅

CAS No.

1354744-91-4

SMILES

O[[email protected]@]1(CC[[email protected]](OCCOCCOCCOCCOCCOCCOCCOC)[[email protected]]2([H])OC3=C4O)[[email protected]]52C3=C(C=C4)C[[email protected]@]1([H])N(CC=C)CC5.OC(C(O)=O)=O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Naloxegol oxalate
Cat. No.:
HY-A0118A
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Naloxegol oxalate

Cat. No.: HY-A0118A