1. GPCR/G Protein
    Neuronal Signaling
  2. Opioid Receptor
  3. Naloxegol

Naloxegol (Synonyms: NKTR-118; AZ-13337019)

Cat. No.: HY-A0118
Handling Instructions

Naloxegol (NKTR-118; AZ-13337019) is a μ-opioid-receptor antagonist. Naloxegol inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation.

For research use only. We do not sell to patients.

Naloxegol Chemical Structure

Naloxegol Chemical Structure

CAS No. : 854601-70-0

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Description

Naloxegol (NKTR-118; AZ-13337019) is a μ-opioid-receptor antagonist. Naloxegol inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation[1][2].

IC50 & Target

Opioid receptor[1]

Clinical Trial
Molecular Weight

651.78

Formula

C₃₄H₅₃NO₁₁

CAS No.

854601-70-0

SMILES

O[[email protected]@]1(CC[[email protected]](OCCOCCOCCOCCOCCOCCOCCOC)[[email protected]]2([H])OC3=C4O)[[email protected]]52C3=C(C=C4)C[[email protected]@]1([H])N(CC=C)CC5

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

NaloxegolNKTR-118AZ-13337019NKTR118NKTR 118AZ13337019AZ 13337019Opioid Receptorμ-opioid-receptoropioid-inducedconstipationOICInhibitorinhibitorinhibit

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