Search Result

Results for "

emodin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (3) Aldose Reductase (2) Antibiotic (2) Apoptosis (1) Autophagy (5) Bacterial (2) Casein Kinase (3) Drug Derivative (1) Drug Metabolite (1) Ferroptosis (2) Fungal (1) Influenza Virus (1) Isotope-Labeled Compounds (1) mTOR (1) p38 MAPK (2) Parasite (1) Phosphatase (4) Reference Standards (6) SARS-CoV (5) SOD (2) Topoisomerase (2) Virus Protease (2)
By Research Areas:	Cancer (7) Cardiovascular Disease (1) Endocrinology (3) Infection (5) Inflammation/Immunology (6) Metabolic Disease (7) Neurological Disease (2)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14393

*Emodin* Maximum Cited Publications 39 Publications Verification Frangula emodin	SARS-CoV Casein Kinase Autophagy 11β-HSD	Cancer
Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC₅₀ of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .

HY-N0189

Aloe emodin 3 Publications Verification Rhabarberone; 3-Hydroxymethylchrysazine	mTOR Influenza Virus Apoptosis Autophagy	Cancer
Aloe emodin (Rhabarberone) is a natural hydroxyanthraquinone with antitumor activities. aloe-emodin can bind with mTORC2 and inhibit its kinase activity. Aloe emodin exerts antiproliferation effects and induces cellular apoptosis . Aloe emodin also exhibits antiviral activity that against influenza A virus .

HY-N0311

Emodin-8-glucoside 2 Publications Verification	Aldose Reductase Topoisomerase SOD p38 MAPK	Neurological Disease Inflammation/Immunology
Emodin-8-glucoside is an anthraquinone derivative that can be isolated from Aloe vera. Emodin-8-glucoside is the inhibitor for MAPK with an inhibition constant of 430.14 pM. Emodin-8-glucoside exhibits moderate inhibitory activity against rat lens aldose reductase (ALAR) and topoisomerases II with IC₅₀s of 14.4 μM and 66 μM. Emodin-8-glucoside exhibits antioxidant, anti-inflammatory and anti-fibrotic activities. Emodin-8-glucoside can cross the blood brain barrier .

HY-N0886

Aloin B 3 Publications Verification Isobarbaloin	SARS-CoV Virus Protease	Infection Endocrinology Cancer
Aloin B (Isobarbaloin) is an orally active SARS-CoV-2 papain-like protease (PLpro) inhibitor with an IC₅₀ of 16.08 μM (hydrolytic activity) and 17.51 μM (deubiquitinase activity). Aloin B is metabolized by rat intestinal flora into aloe-emodin-9-anthrone to exert laxative effects. Aloin B inhibits TPA (HY-18739)-induced ear edema, putrescine elevation, and tumor promotion in mouse skin. Aloin B can be used in research related to anti-inflammation, tumor promotion inhibition, coronavirus disease 2019 (COVID-19) and constipation .

HY-N2394

Emodin-1-O-β-D-glucopyranoside 1 Publications Verification	Bacterial	Inflammation/Immunology
Emodin-1-O-β-D-glucopyranoside, isolated from medicinal plant Polygonum cuspidatum Sieb. & Zucc, is a potent and noncompetitive bacterial neuraminidase (BNA) inhibitor with an IC₅₀ of 0.85 μM .

HY-N2451

*Aloe-emodin-8-O-β-D-glucopyranoside* 1 Publications Verification	Phosphatase	Metabolic Disease Endocrinology
Aloe-emodin-8-O-β-D-glucopyranoside, a compound isolated from Saussrurea lappa, is a moderate inhibitor of human protein tyrosine phosphatase 1B (hPTP1B) with an IC₅₀ of 26.6 μM .

HY-14393R

Emodin (Standard) Maximum Cited Publications 39 Publications Verification Frangula emodin (Standard)	Reference Standards SARS-CoV Casein Kinase Autophagy 11β-HSD	Cancer
Emodin (Standard) is the analytical standard of Emodin. This product is intended for research and analytical applications. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC₅₀ of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .

HY-N9362

Emodinanthrone EmodAN	Ferroptosis Antibiotic	Cardiovascular Disease Infection
Emodinanthrone (EmodAn) is a MARCH7 stabilizer that inhibits ferroptosis (EC₅₀=70 nM). Emodinanthrone is also a precursor to Emodin (HY-14393) and possesses antibiotic activity. Emodinanthrone directly binds to MARCH7 and blocks its ubiquitination-mediated degradation at the K608 site; this action enhances MARCH7-mediated K48 ubiquitination and degradation of NCOA4, as well as its regulation of the intracellular localization of TFR1 via K63 ubiquitination, thereby reducing the intracellular labile iron pool and blocking ferroptosis. Emodinanthrone demonstrates in vivo cardioprotective effects and exhibits a favorable safety profile. Emodinanthrone is applicable to research on ferroptosis-related cardiovascular diseases, including Doxorubicin (HY-15142A)-induced cardiomyopathy and myocardial ischemia-reperfusion injury .

HY-N8344

Frangulin A	Others	Others
Frangulin A is a emodin derivative. Frangulin A can be obtained from Ventilago leiocarpa Benth .

HY-N0189R

*Aloe emodin* (Standard)** 3 Publications Verification Rhabarberone (Standard); 3-Hydroxymethylchrysazine (Standard)	Reference Standards Autophagy	Cancer
Aloe emodin (Standard) is the analytical standard of Aloe emodin. This product is intended for research and analytical applications.

HY-N8126

Emodin 6-O-β-D-glucoside Glucoemodin	Others	Metabolic Disease Inflammation/Immunology
Emodin-6-O-β-D-glucoside (Glucoemodin) is an active compound from Reynoutria japonica. Emodin-6-O-β-D-glucoside shows potent anti-inflammatory and barrier protective effects. Emodin-6-O-β-D-glucoside can be used for the research of diabetic complications and atherosclerosis .

HY-14393S

Emodin-d4 Frangula emodin-d₄	Isotope-Labeled Compounds SARS-CoV Casein Kinase Autophagy 11β-HSD	Cancer
Emodin-d₄ is the deuterium labeled Emodin. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC₅₀ of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .

HY-N5111

*Aloe-emodin-3-(hydroxymethyl)-O-β-D-glucopyranoside* Aloe-emodin 3-O-β-D-glucoside	Others	Others
Aloe-emodin-3-(hydroxymethyl)-O-β-D-glucopyranoside (Aloe-emodin 3-O-β-D-glucoside) is a natural antraquinone .

HY-N16588

*cis-Emodin-physcion bianthrone*	Phosphatase	Metabolic Disease
cis-Emodin-physcion bianthrone is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B), with an IC₅₀ value of 7.29 μM. cis-Emodin-physcion bianthrone can be used for research on type 2 diabetes .

HY-N0311R

Emodin-8-glucoside (Standard)	Reference Standards Aldose Reductase Topoisomerase SOD p38 MAPK	Neurological Disease Inflammation/Immunology
Emodin-8-glucoside (Standard) is the analytical standard of Emodin-8-glucoside. This product is intended for research and analytical applications. Emodin-8-glucoside is an anthraquinone derivative that can be isolated from Aloe vera. Emodin-8-glucoside is the inhibitor for MAPK with an inhibition constant of 430.14 pM. Emodin-8-glucoside exhibits moderate inhibitory activity against rat lens aldose reductase (ALAR) and topoisomerases II with IC₅₀s of 14.4 μM and 66 μM. Emodin-8-glucoside exhibits antioxidant, anti-inflammatory and anti-fibrotic activities. Emodin-8-glucoside can cross the blood brain barrier .

HY-N12256

*cis-Emodin* bianthrone**	Others	Others
Cis-Emodin bianthrone (compound 4) is a highly condensed oxygen of emodin anthrone. Cis-Emodin bianthrone stable in acetone solution in air .

HY-N8143

Emodin-1-O-β-gentiobioside	Others	Metabolic Disease
Emodin-1-O-β-gentiobioside is an anthraquinone .

HY-N12276

*(±)-Emodin* bianthrone**	Parasite Bacterial Fungal	Infection
(±)-Emodin bianthrone (compound 10), a natural product, exhibits antimalarial, antitubercular and ntifungal activities .

HY-N9961

*2-Hydroxyl emodin-1-methyl ether*	Others	Others
2-Hydroxyl emodin-1-methyl ether (Compound 5) is an anthraquinone that can be isolated from the seeds of Cassia obtusifolia .

HY-W353602

*Aleoe-emodin* triacetate**	Drug Derivative	Others
Aleoe-emodin triacetate is an Anthraquinone (HY-N0354) derivative, and can be isolated from leaves of Kniphofia foliosa .

HY-N2451R

*Aloe-emodin-8-O-β-D-glucopyranoside (Standard)*	Reference Standards Phosphatase	Metabolic Disease Endocrinology
Aloe-emodin-8-O-β-D-glucopyranoside (Standard) is the analytical standard of Aloe-emodin-8-O-β-D-glucopyranoside. This product is intended for research and analytical applications. Aloe-emodin-8-O-β-D-glucopyranoside, a compound isolated from Saussrurea lappa, is a moderate inhibitor of human protein tyrosine phosphatase 1B (hPTP1B) with an IC₅₀ of 26.6 μM .

HY-N10322

2-Hydroxyemodin	Drug Metabolite	Others
2-Hydroxyemodin is an active metabolite of emodin in the hepatic microsomes. Emodin is an anthraquinone present in fungal metabolites and constituent of rhubarb. 2-Hydroxyemodin proves to be mutagenic to Salmonella typhimurium TA1537 in the absence of activation system .

HY-N0886R

Aloin B (Standard) Isobarbaloin (Standard)	Reference Standards Virus Protease SARS-CoV	Infection Metabolic Disease Cancer
Aloin B (Isobarbaloin) (Standard) is the analytical standard of Aloin B. This product is intended for research and analytical applications. Aloin B is an orally active SARS-CoV-2 papain-like protease (PLpro) inhibitor with an IC₅₀ of 16.08 μM (hydrolytic activity) and 17.51 μM (deubiquitinase activity). Aloin B is metabolized by rat intestinal flora into aloe-emodin-9-anthrone to exert laxative effects. Aloin B inhibits TPA (HY-18739)-induced ear edema, putrescine elevation, and tumor promotion in mouse skin. Aloin B can be used in research related to anti-inflammation, tumor promotion inhibition, coronavirus disease 2019 (COVID-19) and constipation .

HY-N13348

Emodin-8-O-beta-gentiobioside	Others	Others
Emodin-8-O-beta-gentiobioside is a natural product .

HY-N9362R

Emodinanthrone (Standard) EmodAN (Standard)	Reference Standards Antibiotic Ferroptosis	Infection
Pro-xylane (Standard) is the analytical standard of Pro-xylane. This product is intended for research and analytical applications. Emodinanthrone (EmodAn) is a MARCH7 stabilizer that inhibits ferroptosis (EC₅₀=70 nM). Emodinanthrone is also a precursor to Emodin (HY-14393) and possesses antibiotic activity. Emodinanthrone directly binds to MARCH7 and blocks its ubiquitination-mediated degradation at the K608 site; this action enhances MARCH7-mediated K48 ubiquitination and degradation of NCOA4, as well as its regulation of the intracellular localization of TFR1 via K63 ubiquitination, thereby reducing the intracellular labile iron pool and blocking ferroptosis. Emodinanthrone demonstrates in vivo cardioprotective effects and exhibits a favorable safety profile. Emodinanthrone is applicable to research on ferroptosis-related cardiovascular diseases, including Doxorubicin (HY-15142A)-induced cardiomyopathy and myocardial ischemia-reperfusion injury .

HY-N16588A

*trans-Emodin-physcion bianthrone*	Phosphatase	Metabolic Disease
trans-Emodin-physcion bianthrone is a protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC₅₀ of 2.77 μM. trans-Emodin-physcion bianthrone is applicable to research related to insulin resistance .

HY-N19079

*Rheum emodi* extract**	Others	Inflammation/Immunology
Rheum emodi extract has laxative, anti-inflammatory, and antioxidant properties. Its main active ingredients include anthraquinone compounds (such as emodin, chrysophanol, and aloe-emodin), flavonoids, and tannins.

HY-N18653

Aloe capensis extract	Others	Inflammation/Immunology
Aloe capensis extract is rich in bioactive compounds such as aloe-emodin, plant minerals, vitamins, amino acids, and polysaccharides. It has a strong laxative effect and can be used in research on constipation.

HY-N18716

Senna leaf extract	Others	Others
Senna Leaf Extract is the main raw material of Cassia angustifolia Vahl. Its main active ingredients are Sennoside A and B, and contain rhein, aloe-emodin, chrysophanol and other anthraquinones Derivatives and other glycosides.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-14393

*Emodin* Maximum Cited Publications 39 Publications Verification Frangula emodin	Classification of Application Fields Polygonaceae Plants Endogenous metabolite Quinones Human Gut Microbiota Metabolites Microorganisms Rheum palmatum L. Anthraquinones Phenols Polyphenols Disease Research Fields Source Classification Cancer	SARS-CoV Casein Kinase Autophagy 11β-HSD
Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC₅₀ of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .

HY-N0189

Aloe emodin 3 Publications Verification Rhabarberone; 3-Hydroxymethylchrysazine	Quinones Liliaceae Classification of Application Fields Anthraquinones Phenols Polyphenols Aloe vera (L.) Burm. f. Plants Disease Research Fields Source Classification Cancer	mTOR Influenza Virus Apoptosis Autophagy
Aloe emodin (Rhabarberone) is a natural hydroxyanthraquinone with antitumor activities. aloe-emodin can bind with mTORC2 and inhibit its kinase activity. Aloe emodin exerts antiproliferation effects and induces cellular apoptosis . Aloe emodin also exhibits antiviral activity that against influenza A virus .

HY-N0311

Emodin-8-glucoside 2 Publications Verification	Quinones other families Classification of Application Fields Anthraquinones Phenols Polyphenols Plants Disease Research Fields Source Classification Cancer	Aldose Reductase Topoisomerase SOD p38 MAPK
Emodin-8-glucoside is an anthraquinone derivative that can be isolated from Aloe vera. Emodin-8-glucoside is the inhibitor for MAPK with an inhibition constant of 430.14 pM. Emodin-8-glucoside exhibits moderate inhibitory activity against rat lens aldose reductase (ALAR) and topoisomerases II with IC₅₀s of 14.4 μM and 66 μM. Emodin-8-glucoside exhibits antioxidant, anti-inflammatory and anti-fibrotic activities. Emodin-8-glucoside can cross the blood brain barrier .

HY-N0886

Aloin B 3 Publications Verification Isobarbaloin	Quinones Structural Classification Liliaceae Classification of Application Fields Anthraquinones Other Diseases Phenols Polyphenols Aloe vera (L.) Burm. f. Plants Disease Research Fields Source Classification	SARS-CoV Virus Protease
Aloin B (Isobarbaloin) is an orally active SARS-CoV-2 papain-like protease (PLpro) inhibitor with an IC₅₀ of 16.08 μM (hydrolytic activity) and 17.51 μM (deubiquitinase activity). Aloin B is metabolized by rat intestinal flora into aloe-emodin-9-anthrone to exert laxative effects. Aloin B inhibits TPA (HY-18739)-induced ear edema, putrescine elevation, and tumor promotion in mouse skin. Aloin B can be used in research related to anti-inflammation, tumor promotion inhibition, coronavirus disease 2019 (COVID-19) and constipation .

HY-N2394

Emodin-1-O-β-D-glucopyranoside 1 Publications Verification	Quinones Rheum palmatum L. Classification of Application Fields Anthraquinones Polygonaceae Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Source Classification	Bacterial
Emodin-1-O-β-D-glucopyranoside, isolated from medicinal plant Polygonum cuspidatum Sieb. & Zucc, is a potent and noncompetitive bacterial neuraminidase (BNA) inhibitor with an IC₅₀ of 0.85 μM .

HY-N2451

*Aloe-emodin-8-O-β-D-glucopyranoside* 1 Publications Verification	Quinones Monophenols Liliaceae Classification of Application Fields Anthraquinones Phenols Aloe vera (L.) Burm. f. Metabolic Disease Plants Disease Research Fields Source Classification	Phosphatase
Aloe-emodin-8-O-β-D-glucopyranoside, a compound isolated from Saussrurea lappa, is a moderate inhibitor of human protein tyrosine phosphatase 1B (hPTP1B) with an IC₅₀ of 26.6 μM .

HY-14393R

Emodin (Standard) Maximum Cited Publications 39 Publications Verification Frangula emodin (Standard)	Quinones Rheum palmatum L. Classification of Application Fields Polygonaceae Phenols Plants Disease Research Fields Source Classification Cancer	Reference Standards SARS-CoV Casein Kinase Autophagy 11β-HSD
Emodin (Standard) is the analytical standard of Emodin. This product is intended for research and analytical applications. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC₅₀ of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .

HY-N9362

Emodinanthrone EmodAN	Infection Structural Classification Classification of Application Fields Phenols Polyphenols Plants Rhamnaceae Aconitum nagarum var. acaule (Finet & Gagnep.) Q. E. Yang Disease Research Fields Source Classification	Ferroptosis Antibiotic
Emodinanthrone (EmodAn) is a MARCH7 stabilizer that inhibits ferroptosis (EC₅₀=70 nM). Emodinanthrone is also a precursor to Emodin (HY-14393) and possesses antibiotic activity. Emodinanthrone directly binds to MARCH7 and blocks its ubiquitination-mediated degradation at the K608 site; this action enhances MARCH7-mediated K48 ubiquitination and degradation of NCOA4, as well as its regulation of the intracellular localization of TFR1 via K63 ubiquitination, thereby reducing the intracellular labile iron pool and blocking ferroptosis. Emodinanthrone demonstrates in vivo cardioprotective effects and exhibits a favorable safety profile. Emodinanthrone is applicable to research on ferroptosis-related cardiovascular diseases, including Doxorubicin (HY-15142A)-induced cardiomyopathy and myocardial ischemia-reperfusion injury .

HY-N8344

Frangulin A	Ventilago leiocarpa Benth. Quinones Anthraquinones Plants Rhamnaceae Source Classification	Others
Frangulin A is a emodin derivative. Frangulin A can be obtained from Ventilago leiocarpa Benth .

HY-N0189R

*Aloe emodin* (Standard)** 3 Publications Verification Rhabarberone (Standard); 3-Hydroxymethylchrysazine (Standard)	Quinones Liliaceae Classification of Application Fields Phenols Aloe vera (L.) Burm. f. Plants Disease Research Fields Source Classification Cancer	Reference Standards Autophagy
Aloe emodin (Standard) is the analytical standard of Aloe emodin. This product is intended for research and analytical applications.

HY-N8126

Emodin 6-O-β-D-glucoside Glucoemodin	Quinones Classification of Application Fields Anthraquinones Polygonaceae Reynoutria japonica Houtt. Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Source Classification	Others
Emodin-6-O-β-D-glucoside (Glucoemodin) is an active compound from Reynoutria japonica. Emodin-6-O-β-D-glucoside shows potent anti-inflammatory and barrier protective effects. Emodin-6-O-β-D-glucoside can be used for the research of diabetic complications and atherosclerosis .

HY-N5111

*Aloe-emodin-3-(hydroxymethyl)-O-β-D-glucopyranoside* Aloe-emodin 3-O-β-D-glucoside	Quinones Classification of Application Fields Anthraquinones Polygonaceae Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Others
Aloe-emodin-3-(hydroxymethyl)-O-β-D-glucopyranoside (Aloe-emodin 3-O-β-D-glucoside) is a natural antraquinone .

HY-N16588

*cis-Emodin-physcion bianthrone*	Structural Classification Leguminosae Senna Mill. Phenols Polyphenols Plants Senna tora (L.) Roxb. Source Classification	Phosphatase
cis-Emodin-physcion bianthrone is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B), with an IC₅₀ value of 7.29 μM. cis-Emodin-physcion bianthrone can be used for research on type 2 diabetes .

HY-N0311R

Emodin-8-glucoside (Standard)	Quinones Structural Classification other families Anthraquinones Phenols Polyphenols Plants Source Classification	Reference Standards Aldose Reductase Topoisomerase SOD p38 MAPK
Emodin-8-glucoside (Standard) is the analytical standard of Emodin-8-glucoside. This product is intended for research and analytical applications. Emodin-8-glucoside is an anthraquinone derivative that can be isolated from Aloe vera. Emodin-8-glucoside is the inhibitor for MAPK with an inhibition constant of 430.14 pM. Emodin-8-glucoside exhibits moderate inhibitory activity against rat lens aldose reductase (ALAR) and topoisomerases II with IC₅₀s of 14.4 μM and 66 μM. Emodin-8-glucoside exhibits antioxidant, anti-inflammatory and anti-fibrotic activities. Emodin-8-glucoside can cross the blood brain barrier .

HY-N12256

*cis-Emodin* bianthrone**	Quinones Anthraquinones Guttiferae Plants Source Classification Hypericum monogynum L.	Others
Cis-Emodin bianthrone (compound 4) is a highly condensed oxygen of emodin anthrone. Cis-Emodin bianthrone stable in acetone solution in air .

HY-N8143

Emodin-1-O-β-gentiobioside	Quinones Classification of Application Fields Anthraquinones Phenols Polyphenols Caesalpiniaceae Cassia obtusifolia (L.) H. S. Irwin & Barneby Metabolic Disease Plants Disease Research Fields Source Classification	Others
Emodin-1-O-β-gentiobioside is an anthraquinone .

HY-N12276

*(±)-Emodin* bianthrone**	Microorganisms Phenols Polyphenols Source Classification	Parasite Bacterial Fungal
(±)-Emodin bianthrone (compound 10), a natural product, exhibits antimalarial, antitubercular and ntifungal activities .

HY-N9961

*2-Hydroxyl emodin-1-methyl ether*	Quinones Anthraquinones Caesalpiniaceae Cassia obtusifolia (L.) H. S. Irwin & Barneby Plants Source Classification	Others
2-Hydroxyl emodin-1-methyl ether (Compound 5) is an anthraquinone that can be isolated from the seeds of Cassia obtusifolia .

HY-W353602

*Aleoe-emodin* triacetate**	Quinones Anthraquinones Plants Asphodelaceae Kniphofia foliosa Hochst. Source Classification	Drug Derivative
Aleoe-emodin triacetate is an Anthraquinone (HY-N0354) derivative, and can be isolated from leaves of Kniphofia foliosa .

HY-N2451R

*Aloe-emodin-8-O-β-D-glucopyranoside (Standard)*	Quinones Structural Classification Monophenols Liliaceae Anthraquinones Phenols Aloe vera (L.) Burm. f. Plants Source Classification	Reference Standards Phosphatase
Aloe-emodin-8-O-β-D-glucopyranoside (Standard) is the analytical standard of Aloe-emodin-8-O-β-D-glucopyranoside. This product is intended for research and analytical applications. Aloe-emodin-8-O-β-D-glucopyranoside, a compound isolated from Saussrurea lappa, is a moderate inhibitor of human protein tyrosine phosphatase 1B (hPTP1B) with an IC₅₀ of 26.6 μM .

HY-N10322

2-Hydroxyemodin	Quinones other families Classification of Application Fields Anthraquinones Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Drug Metabolite
2-Hydroxyemodin is an active metabolite of emodin in the hepatic microsomes. Emodin is an anthraquinone present in fungal metabolites and constituent of rhubarb. 2-Hydroxyemodin proves to be mutagenic to Salmonella typhimurium TA1537 in the absence of activation system .

HY-N0886R

Aloin B (Standard) Isobarbaloin (Standard)	Quinones Structural Classification Liliaceae Anthraquinones Phenols Polyphenols Aloe vera (L.) Burm. f. Plants Source Classification	Reference Standards Virus Protease SARS-CoV
Aloin B (Isobarbaloin) (Standard) is the analytical standard of Aloin B. This product is intended for research and analytical applications. Aloin B is an orally active SARS-CoV-2 papain-like protease (PLpro) inhibitor with an IC₅₀ of 16.08 μM (hydrolytic activity) and 17.51 μM (deubiquitinase activity). Aloin B is metabolized by rat intestinal flora into aloe-emodin-9-anthrone to exert laxative effects. Aloin B inhibits TPA (HY-18739)-induced ear edema, putrescine elevation, and tumor promotion in mouse skin. Aloin B can be used in research related to anti-inflammation, tumor promotion inhibition, coronavirus disease 2019 (COVID-19) and constipation .

HY-N13348

Emodin-8-O-beta-gentiobioside	Quinones Rheum palmatum L. Anthraquinones Polygonaceae Plants Source Classification	Others
Emodin-8-O-beta-gentiobioside is a natural product .

HY-N9362R

Emodinanthrone (Standard) EmodAN (Standard)	Structural Classification Phenols Polyphenols Plants Rhamnaceae Aconitum nagarum var. acaule (Finet & Gagnep.) Q. E. Yang Source Classification	Reference Standards Antibiotic Ferroptosis
Pro-xylane (Standard) is the analytical standard of Pro-xylane. This product is intended for research and analytical applications. Emodinanthrone (EmodAn) is a MARCH7 stabilizer that inhibits ferroptosis (EC₅₀=70 nM). Emodinanthrone is also a precursor to Emodin (HY-14393) and possesses antibiotic activity. Emodinanthrone directly binds to MARCH7 and blocks its ubiquitination-mediated degradation at the K608 site; this action enhances MARCH7-mediated K48 ubiquitination and degradation of NCOA4, as well as its regulation of the intracellular localization of TFR1 via K63 ubiquitination, thereby reducing the intracellular labile iron pool and blocking ferroptosis. Emodinanthrone demonstrates in vivo cardioprotective effects and exhibits a favorable safety profile. Emodinanthrone is applicable to research on ferroptosis-related cardiovascular diseases, including Doxorubicin (HY-15142A)-induced cardiomyopathy and myocardial ischemia-reperfusion injury .

HY-N16588A

*trans-Emodin-physcion bianthrone*	Structural Classification Xanthones Polygonaceae Reynoutria japonica Houtt. Phenols Plants Source Classification	Phosphatase
trans-Emodin-physcion bianthrone is a protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC₅₀ of 2.77 μM. trans-Emodin-physcion bianthrone is applicable to research related to insulin resistance .

HY-N19079

*Rheum emodi* extract**	Structural Classification Extract	Others
Rheum emodi extract has laxative, anti-inflammatory, and antioxidant properties. Its main active ingredients include anthraquinone compounds (such as emodin, chrysophanol, and aloe-emodin), flavonoids, and tannins.

HY-N18653

Aloe capensis extract	Structural Classification Extract	Others
Aloe capensis extract is rich in bioactive compounds such as aloe-emodin, plant minerals, vitamins, amino acids, and polysaccharides. It has a strong laxative effect and can be used in research on constipation.

HY-N18716

Senna leaf extract	Structural Classification Extract	Others
Senna Leaf Extract is the main raw material of Cassia angustifolia Vahl. Its main active ingredients are Sennoside A and B, and contain rhein, aloe-emodin, chrysophanol and other anthraquinones Derivatives and other glycosides.

Cat. No.	Product Name	Chemical Structure

HY-14393S

Emodin-d4

Emodin-d₄ is the deuterium labeled Emodin. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC₅₀ of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

emodin

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products