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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
65 Results for "
glucose-regulated
" in MedChemExpress (MCE) Product Catalog:
Products (65)
65 Results for "glucose-regulated" in MCE Product Catalog:
116
116
4
4 Cited Publications
YUM70 is a potent and selective inhibitor of glucose-regulated protein 78 (GRP78), with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer. YUM70 also has in vivo efficacy in a pancreatic cancer xenograft model .
3
3 Cited Publications
Cat. No.: HY-N0830S6
CAS No.: 56599-85-0
3
3 Cited Publications
Cat. No.: HY-N0830BS1
CAS No.: 2483736-17-8
3
3 Cited Publications
Cat. No.: HY-W134007S1
CAS No.: 1458714-74-3
1
1 Cited Publications
Cat. No.: HY-161834
CAS No.: 2140901-88-6
Research Areas:
RG100204 is a selective, orally available inhibitor of the aquaporin AQP9. RG100204 directly inhibits AQP9 channel function, preventing the transmembrane transport of water, glycerol, and H 2O 2. RG100204 reduces the activation of the NLRP3 inflammasome and p38 MAPK signaling pathways, thereby alleviating inflammation and pyroptosis. RG100204 reduces multi-organ dysfunction in a mouse sepsis model and shows glucose-regulating effects in diabetic db/db mice .
1
1 Cited Publications
Cat. No.: HY-N0830S18
CAS No.: 358730-99-1
1
1 Cited Publications
Cat. No.: HY-N0830S3
CAS No.: 57677-53-9
1
1 Cited Publications
Cat. No.: HY-N0830S12
CAS No.: 75736-47-9
1
1
1 Cited Publications
Cat. No.: HY-P80496
Synonyms: GRP78, HSPA5, Endoplasmic reticulum chaperone BiP, 78 kDa glucose-regulated protein, Binding-immunoglobulin protein, Heat shock protein 70 family protein 5, Heat shock protein family A member 5, Immunoglobulin heavy chain-binding protein, GRP-78, BiP, HSP70 family protein 5
Cat. No.: HY-N0830S2
CAS No.: 39756-30-4
Cat. No.: HY-N0830S9
CAS No.: 287100-87-2
Cat. No.: HY-N0830S5
CAS No.: 75736-53-7
Cat. No.: HY-N0830S4
CAS No.: 62689-96-7
Cat. No.: HY-N0830S7
CAS No.: 75736-49-1
Cat. No.: HY-N0830S
CAS No.: 287100-89-4
Cat. No.: HY-N5073
CAS No.: 178468-00-3
Synonyms: 4''-O-Glucosylvitexin
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
