2 Results for "

glycogenosis type II

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "glycogenosis type II" in MCE Product Catalog:

Cat. No.: HY-E70183
Synonyms: EC:3.2.1.20; GAA
Lysosomal α-Glucosidase (EC:3.2.1.20) is a lysosomal α-Glucosidase that degrades glycogen into glucose and catalyzes the hydrolysis of α-1,4 and α-1,6 glycosidic linkages in glycogen, as well as that of natural and synthetic oligoglucosides. Deficiency of Lysosomal α-Glucosidase causes type II glycogen storage disease (Pompe disease), which is characterized by lysosomal glycogen accumulation in mammals and birds. Lysosomal α-Glucosidase can be used in research related to type II glycogen storage disease .
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Cat. No.: HY-178202
CAS No.: 2734265-58-6
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

5-C-phenethyl-DNJ is a selective α-glucosidase GAA inhibitor, with its Ki value for rhGAA being 0.81 μM. 5-C-phenethyl-DNJ exhibits extremely high selectivity for GANAB, GBA1, and GBA2. 5-C-phenethyl-DNJ can be used for the study of Pompe disease .
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