29 Results for "

human CD22

" in MedChemExpress (MCE) Product Catalog:
Products (29)

29 Results for "human CD22" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99264
CAS No.: 1660159-36-3
Synonyms: humanized Anti-CD22 Recombinant Antibody

Research Areas:  

Cancer

Inotuzumab (Humanized Anti-CD22 Recombinant Antibody) is a humanized IgG4κ antibody that targets human CD22. Inotuzumab can be linked to a toxic agent Ozogamicin as an antibody-drug conjugate (ADC), Inotuzumab ozogamicin (HY-P9959). Inotuzumab can be used for the research of acute lymphoblastic leukemia and non-Hodgkin lymphoma .
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Cat. No.: HY-P9959
CAS No.: 635715-01-4
Synonyms: CMC-544; PF-5208773; WAY-207294
Research Areas:  

Cancer

Inotuzumab ozogamicin (CMC-544) is an antibody-targeted chemotherapy agent composed of a humanized anti-CD22 antibody Inotuzumab (HY-P99264) conjugated to Calicheamicin (HY-19609). Inotuzumab ozogamicin and G544 bind human CD22 with similar affinities (Kd ≈ 150 pM). Inotuzumab ozogamicin has demonstrated efficacy against CD22 + B-cell non-Hodgkin’s lymphoma. Inotuzumab ozogamicin can be used in the research of acute lymphoblastic leukemia .
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Cat. No.: HY-132250
CAS No.: 1100692-14-5
Purity:  99.52%
Research Areas:  

Cancer

MCC-DM1 is a agent-Linker Conjugates for ADC such as Anti-CD22-MCC-DM1. MCC-DM1 can be detected in rat and human plasma, feces, and other tissues .
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Cat. No.: HY-P99230
CAS No.: 1639820-81-7

Target:  

Integrin CD22

Research Areas:  

Cancer

Pinatuzumab is a humanized monoclonal antibody targeting cell-surface antigen CD22. Pinatuzumab can be used to synthesize antibody-drug conjugate (ADC) such as Pinatuzumab vedotin (HY-141602). Pinatuzumab can be studied in research on cancer such as non-Hodgkin lymphoma. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P991550
CAS No.: 505393-48-6

Target:  

CD22

Research Areas:  

Cancer

RFB4 is an anti-CD22 monoclonal antibody. RFB4 can be fused with Pseudomonas aeruginosa exotoxin (PE38) via disulfide bonds to construct recombinant immunotoxins, such as RFB4 (dsFv)-PE38. RFB4 is applicable to the research of cancers including lymphoma .
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Cat. No.: HY-RS02210
Research Areas:  

Others

CD22 Human Pre-designed siRNA Set A contains three designed siRNAs for CD22 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P99264A
CAS No.: 1660159-36-3
Synonyms: humanized Anti-CD22 Recombinant Antibody (powder)

Research Areas:  

Cancer

Inotuzumab (Humanized Anti-CD22 Recombinant Antibody) (powder) is a humanized IgG4κ antibody that targets human CD22. Inotuzumab (powder) can be linked to a toxic agent Ozogamicin as an antibody-drug conjugate (ADC), Inotuzumab ozogamicin (HY-P9959). Inotuzumab (powder) can be used for the research of acute lymphoblastic leukemia and non-Hodgkin lymphoma .
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Cat. No.: HY-P990781
CAS No.: 2415439-63-1
Synonyms: SM03
Suciraslimab (SM03) is an anti-human CD22 monoclonal antibody. Suciraslimab inhibits NLRP3 and ASC signaling. Suciraslimab suppresses cytokine (IL-1β, IL-12, IL-23) secretion and α4 integrin expression. Suciraslimab improves working memory and neuroinflammation . Suciraslimab isotype control product: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-146081
CAS No.: 2493080-27-4
Target:  

CD22 Drug Intermediate

Research Areas:  

Inflammation/Immunology Cancer

CD22 ligand-1 is a CD22-selective ligand with a Kd value of 0.335 μM for human CD22. CD22 ligand-1 binds to CD22 with high affinity and can be used for drug conjugation to achieve B cell targeting or multimer formation. CD22 ligand-1 is applicable to the study of B cell-mediated autoimmune diseases and B cell-associated lymphomas .
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Cat. No.: HY-P990759
CAS No.: 2795115-07-8
Synonyms: JNJ-75348780

Target:  

CD22 CD3

Research Areas:  

Inflammation/Immunology

Rezetamig is a human bispecific antibody that recognizes the CD3 antigen on T-lymphocytes and the CD22 antigen on mature and malignant B-lymphocytes .
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Cat. No.: HY-P990506
Synonyms: NCI m971

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-Siglec-2/CD22 Antibody (NCI m971) is a humanized antibody expressed in CHO cells that targets Siglec-2/CD22. Anti-Siglec-2/CD22 Antibody (NCI m971) features a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 146.64 kDa. The isotype control for Anti-Siglec-2/CD22 Antibody (NCI m971) can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990930
CAS No.: 2852752-92-0
Synonyms: AB-125
HY-P990930 is an CD22-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P990507
Synonyms: NCI m972

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

The Anti-Siglec-2/CD22 Antibody (NCI m972) is a humanized antibody expressed in CHO, targeting Siglec-2/CD22. The Anti-Siglec-2/CD22 Antibody (NCI m972) has a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 144.3 kDa. The isotype control for Anti-Siglec-2/CD22 Antibody (NCI m972) can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P9959A
CAS No.: 635715-01-4
Synonyms: CMC-544 (solution); PF-5208773 (solution); WAY-207294 (solution)
Research Areas:  

Cancer

Inotuzumab ozogamicin solution (CMC-544 solution) is an antibody-targeted chemotherapy agent composed of a humanized anti-CD22 antibody conjugated to Calicheamicin (HY-19609). Inotuzumab ozogamicin solution and G544 bind human CD22 with similar affinities (Kd ≈ 150 pM). Inotuzumab ozogamicin solution has demonstrated efficacy against CD22 + B-cell non-Hodgkin’s lymphoma. Inotuzumab ozogamicin solution can be used in the research of acute lymphoblastic leukemia .
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Cat. No.: HY-P70560
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P72019
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P72351
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P77537
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78541
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704294
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Human
Source:  
HEK293
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