CD22 ligand-1
CD22 ligand-1 is a CD22-selective ligand with a Kd value of 0.335 μM for human CD22. CD22 ligand-1 binds to CD22 with high affinity and can be used for drug conjugation to achieve B cell targeting or multimer formation. CD22 ligand-1 is applicable to the study of B cell-mediated autoimmune diseases and B cell-associated lymphomas.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2493080-27-4
- 分子式: C33H34N5NaO10
- 分子量:683.64
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
KD: 0.335 µM (hCD22); 30.7 µM (MAG)[1]
体外実験
CD22 ligand-1 (compound 12) (2 min association, 3 min dissociation) binds potently to recombinant human CD22 with a Kd value of 0.335 μM, and exhibits 91.6-fold selectivity over recombinant human MAG[1].
CD22 ligand-1 binds to human CD22 CRD more strongly and stably than to human MAG CRD[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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CAS 番号 2493080-27-4
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分子量 683.64
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分子式 C33H34N5NaO10
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SMILES
O=C([C@]1(N2C=C(C3=CC=CC=C3)N=N2)O[C@@]([C@@H]([C@H](C1)O)NC(CO)=O)([H])[C@H](O)[C@H](O)CNC(CC4=CC=C(C5=CC=C(C=C5)O)C=C4)=O)O[Na]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
CD22 ligand-1 関連分類
HY-146081 関連分類
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