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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
human TMEM175
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "human TMEM175" in MCE Product Catalog:
Cat. No.: HY-162666
CAS No.: 3038770-25-8
Target:
Research Areas:
TMEM175 modulator 1 (compound 47) is a TMEM175 modulator.TMEM175 modulator 1 modulates activity of the lysosomal potassium ion channel TMEM175.TMEM175 modulator 1 can be used for the research of parkinson’s disease, dementia, alzheimer’s disease, l-dopa induced dyskinesia .
Cat. No.: HY-RS14683
Target:
Research Areas:
TMEM175 Human Pre-designed siRNA Set A contains three designed siRNAs for TMEM175 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-186253
CAS No.: 3129653-69-3
Target:
Research Areas:
TMEM175 agonist 1 is a TMEM175 agonist, with a human EC50 of 0.378 μM in FLIPR assays and a human EC50 of 0.886 μM in EP analyses. TMEM175 agonist 1 can be used in the research of Parkinson's disease, dementia with Lewy bodies, rapid eye movement sleep behavior disorder, amyotrophic lateral sclerosis, and lysosomal storage diseases .
Cat. No.: HY-186257
CAS No.: 3129652-66-7
Target:
Research Areas:
TMEM175 agonist 3 (Compound 123) is a TMEM175 agonist, with an EC50 of 0.044 μM in human TMEM175 FLIPR assays and an EC50 of 0.073 μM in human TMEM175 EP assays. TMEM175 agonist 3 can be used in the research of Parkinson's disease, dementia with Lewy bodies, rapid eye movement sleep behavior disorder, amyotrophic lateral sclerosis, and lysosomal storage diseases .
Cat. No.: HY-186254
CAS No.: 3129652-92-9
Target:
Research Areas:
TMEM175 agonist 2 is a TMEM175 agonist with an EC50 of 0.0446 μM in human FLIPR assays and an EC50 of 0.0453 μM in human TMEM175 EP assays. TMEM175 agonist 2 can be used in research related to Parkinson's disease, dementia with Lewy bodies, rapid eye movement sleep behavior disorder, amyotrophic lateral sclerosis, and lysosomal storage diseases .
Cat. No.: HY-P703367
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Endosomal/lysosomal proton channel TMEM175; Potassium channel TMEM175; Transmembrane protein 175; hTMEM175; TMEM175; Homo sapiens; human; Ion channel; Potassium channel
Cat. No.: HY-P703368
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Endosomal/lysosomal proton channel TMEM175; Potassium channel TMEM175; Transmembrane protein 175; hTMEM175; TMEM175; Homo sapiens; human; Ion channel; Potassium channel
Cat. No.: HY-182464
CAS No.: 893603-33-3
Target:
DABMA is a TMEM175 channel activator with a human EC50 of 17.9 μM. DABMA directly increases TMEM175 channel current via interaction with intracellular, transmembrane, or endosomal lumen-associated domains, and does not alter TMEM175 mRNA or protein levels. DABMA delays endolysosomal substrate degradation, modulates endolysosomal trafficking, increases acidic organelle accumulation, induces cholesterol accumulation and altered late endosome morphology. DABMA can be used for the research of coronavirus disease, Clostridium difficile infection, Pseudomonas aeruginosa infection, rabies, and influenza virus infection .
Cat. No.: HY-186259
Target:
Research Areas:
TMEM175 agonist 5 (Compound 252) is a TMEM175 agonist with an EC50 of 421 nM in FLIPR cell assays. TMEM175 agonist 5 can be used for the research of neurodegenerative diseases and lysosomal storage disorders .
Cat. No.: HY-186261
Target:
Research Areas:
TMEM175 agonist 7 is a TMEM175 agonist with an EC50 of 543 nM. TMEM175 agonist 7 is applicable to the research of neurodegenerative diseases and lysosomal storage disorders .
Cat. No.: HY-186258
Target:
Research Areas:
TMEM175 agonist 4 (Compound 276) is a TMEM175 agonist. TMEM175 agonist 4 can be used for the research of neurodegenerative diseases and lysosomal storage diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
